The oxidation processes of the radiation-generated, three-electron-bonded intermediates AcMet2 [S∴S]+ and AcMet [S∴Br] were investigated by pulse radiolysis via their reactions with tryptophan (TrpH). These intermediates were derived from N-acetyl-methionine amide (N-AcMetNH2) and N-acetyl-methionine methyl ester (N-AcMetOMe). The bimolecular rate constant k of the reaction between each intermediate and l-tryptophan (TrpH) was measured. For N-AcMetNH2, k for the reaction of AcMet2 [S∴S]+ with TrpH were 3.4 × 108 and 2.2 × 108 dm3 mol−1 s−1 at pH = 1 and 4.5, respectively. For N-AcMetOMe, k for the reaction of AcMet2 [S∴S]+ with TrpH were 4.0 × 108 and 2.8 × 108 dm3 mol−1 s−1 at pH 1 and 4.5, respectively. The rate constants for the intermolecular transformation of Met [S∴Br] into TrpH+ or Trp were also estimated. For N-AcMetNH2, k for the reaction of AcMet2 [S∴Br] with TrpH were 2.6 × 108 and 3.3 × 108 dm3 mol−1 s−1 at pH 1 and 4.5, respectively. Related mechanisms were discussed.
Research on Chemical Intermediates – Springer Journals
Published: Jun 14, 2011
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera