PharmacoEconomics & Outcomes News 792, p25 - 2 Dec 2017 Publicly funded opioid abuse therapy cost effective in USA Publicly funded opioid abuse therapy (OAT) appears to be cost effective, according to findings of a US study published in Annals of Internal Medicine. A semi-Markov model was used to evaluate the cost effectiveness and budget impact of immediate access to opioid abuse therapy with methadone in a hypothetical population of patients 35 years of age with opioid abuse disorder (primarily due to heroin) presenting at publicly funded treatment centers in California, compared with the standard of care (short- term medically managed withdrawal), from a societal perspective over a lifetime time horizon. The model was populated with data from linked treatment and criminal justice administrative databases. Immediate access to opioid abuse therapy was estimated to gain 0.42 additional QALYs compared with the standard of care and to reduce total costs by $78 257 over a lifetime. Opioid abuse therapy was therefore dominant (more effective and less costly). It was estimated that treatment of all patients with opioid use disorder in California in 2014 with immediate opioid abuse therapy would achieve total lifetime savings $3.8 billion. Sensitivity analysis found that opioid abuse therapy was cost effective in 99.6% of simulations. "Our findings further underline the need for widespread and unencumbered access to evidence- based treatment of opioid use disorder to reduce the burden to society of the current prescription opioid and heroin use epidemic," the authors commented. * 2016 US dollars Krebs E, et al. Cost-Effectiveness of Publicly Funded Treatment of Opioid Use Disorder in California Annals of Internal Medicine : 21 Nov 2017. Available from: URL: http://doi.org/10.7326/M17-0611 803284965 1173-5503/17/0792-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved PharmacoEconomics & Outcomes News 2 Dec 2017 No. 792
PharmacoEconomics & Outcomes News – Springer Journals
Published: Dec 2, 2017
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