The key elements of the regulatory system activating expression of the lux-operon genes in the marine bacteria Vibrio fischeri are the LuxR protein (an activator of transcription) and N-(3-oxohexanoyl) L-homoserine lactone (an autoinducer, AI). It is shown that the ATP-dependent proteases ClpXP and Lon take part in the negative control of expression of the lux-operon genes and that AI protects the LuxR protein from proteolysis.
Russian Journal of Genetics – Springer Journals
Published: Aug 17, 2010
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