Plant Molecular Biology 33: 771–789, 1997. 771 1997 Kluwer Academic Publishers. Printed in Belgium. Mini-review 1 2; James Whelan and Elzbieta Glaser Department of Biochemistry, University of Western Australia, Nedlands, 6907 Perth, Western Australia, Australia; Department of Biochemistry, Arrhenius Laboratories for Natural Sciences, Stockholm University, 106 91 Stockholm, Sweden ( Author for correspondence) Received and accepted 6 November 1996 Introduction General characteristics of the mitochondrial protein import process The import of proteins into mitochondria was ﬁrst reported in 1977 in Neurospora crassa using both in The mitochondrial genome encodes for only a hand- vitro and in vivo techniques [72, 73]. An immense ful of mitochondrial proteins. Several hundred mito- amount of research on the protein import process has chondrial proteins are encoded in the nucleus, syn- been performed since then, especially in fungi, where thesised in the cytosol and imported into mitochon- several proteins involved in the import process have dria. The protein import process into mitochondria been sequenced and their role analysed by genetic can be divided into several steps: (1) synthesis and inactivation (see [75, 108, 128, 143] for reviews) . maintenance of the import competent conformation of The characterisation of the plant mitochondrial protein the precursor
Plant Molecular Biology – Springer Journals
Published: Sep 29, 2004
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