Prostate cancer incidence as an iceberg

Prostate cancer incidence as an iceberg Eur J Epidemiol (2017) 32:477–479 DOI 10.1007/s10654-017-0265-8 COMMENTARY 1,2,3 1 1 4 • • • • Lorelei A. Mucci Claire H. Pernar Sam Peisch Travis Gerke 1,2 Kathryn M. Wilson Received: 5 May 2017 / Accepted: 23 May 2017 / Published online: 30 May 2017 Springer Science+Business Media Dordrecht 2017 The epidemiology of prostate cancer is enigmatic. Glob- authors focus nicely on the ‘‘natural experiment’’ of PSA ally, 1.6 million men were diagnosed with prostate cancer screening, first introduced in the United States (US) in the in 2015 [1], a notable 66% rise in its incidence from the late 1980s and in other countries (including Norway) in the prior 10 years. It is the most commonly diagnosed cancer 1990s, and how its uptake has altered the diagnosis of this in men in 103 countries, yet there is marked variation in disease. The authors show that PSA screening has led to the age-adjusted incidence rates across countries and popula- characteristic patterns of prostate cancer incidence rates in tions. A panel of epidemiologists are likely to agree only Norway and the US; with rates increasing soon after on the following risk factors as ‘‘established’’: older age, screening was introduced in these European Journal of Epidemiology Springer Journals

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Springer Netherlands
Copyright © 2017 by Springer Science+Business Media Dordrecht
Medicine & Public Health; Epidemiology; Public Health; Infectious Diseases; Cardiology; Oncology
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