Graefes Arch Clin Exp Ophthalmol (2017) 255:1551–1558 DOI 10.1007/s00417-017-3693-y RETINAL DISORDERS Proposal of a simple optical coherence tomography-based scoring system for progression of age-related macular degeneration 1,2,3 1,2 1,2 Jianqin Lei & Siva Balasubramanian & Nizar Saleh Abdelfattah & 1,2 1,2 Muneeswar G. Nittala & SriniVas R. Sadda Received: 15 November 2016 /Revised: 3 May 2017 /Accepted: 8 May 2017 /Published online: 22 May 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract category assignment with progression to late AMD (defined Purpose To develop a simple, clinically practical, optical co- as the presence of atrophy or CNVon OCT) by the last follow- herence tomography (OCT)-based scoring system for early up visit was evaluated with logistic regression analysis. age-related macular degeneration (AMD) to prognosticate risk Results The rate of progression to late AMD was 39.9% (55/ for progression to late AMD. 138). Progression rates by category (I to IV) were 0, 14.3, Methods We retrospectively reviewed OCT images 47.5, and 73.3%, respectively. Logistic regression analysis (512 × 128 macular cube, Cirrus) from 138 patients diagnosed showed risk of progression to late AMD was 3.0 times (95% of early AMD in at least one eye and follow-up of at least CI: 1.2–7.9) higher for
Graefe's Archive for Clinical and Experimental Ophthalmology – Springer Journals
Published: May 22, 2017
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