ISSN 1070-4272, Russian Journal of Applied Chemistry, 2007, Vol. 80, No. 5, pp. 771!776. + Pleiades Publishing, Ltd., 2007.
Original Russian Text + L.I. Kutsenko, Yu.G. Santuryan, E.B. Karetnikova, I.V. Gofman, A.M. Bochek, E.F. Panarin, 2007, published in Zhurnal
Prikladnoi Khimii, 2007, Vol. 80, No. 5, pp. 792!797.
AND POLYMERIC MATERIALS
Properties of the Methyl Cellulose!Polyvinylpyrrolidone
Binary System in Solution and in the Solid State
L. I. Kutsenko, Yu. G. Santuryan, E. B. Karetnikova, I. V. Gofman,
A. M. Bochek, and E. F. Panarin
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Received March 21, 2007
Abstract-Rheological properties of dilute and moderately concentrated aqueous solutions of methyl cellu-
lose3polyvinylpyrrolidone blends, as well as the conditions of gelation in them, were studied. Films were ob-
tained from solutions of the polymer blends, and their physicomechanical properties were examined. The range
of the compositions corresponding to thermodynamic compatibility of methyl cellulose with polyvinylpyrroli-
done was identified by the solvent vapor sorption method and by thermomechanical examinations of the films.
Preparation of cellulose materials with novel or
improved properties through combining cellulose
ethers with synthetic polymers is of scientific and
practical interest. Structural modification of polymers
by combining two polymers of different chemical
structures in a common solvent allows preparation of
polymer blends with controllable properties. Depend-
ing on the chemical composition, rigidity of the
macromolecular chain, degree of polymerization,
and kind of solvent, the blended polymers can form
in solution structures of different organization and
Increased attention is given today to self-associated
polymer systems based on environmentally safe and
biodegradable natural polymers . Among these
polymers are water-soluble compounds of cellulose:
sodium salt of carboxymethyl cellulose (NaCMC),
methyl cellulose (MC), and other ethers [2, 3]. Methyl
cellulose is widely used as thickener of muds in oil
extraction, as well as in textile, pulp and paper, food,
and pharmaceutical industries . The rheological
properties of MC solutions and conditions of gelation
in them, as well as the physicomechanical properties
of the films obtained from solutions, can also be
varied by introducing a different water-soluble poly-
mer into solutions .
Polyvinylpyrrolidone (PVP) is used in production
of tableted medicines and also serves as blood sub-
stitute and blood detoxifier. It is used for preparing
prolonged-action agents with a wide activity spectrum
In this study we examined the rheological proper-
ties of dilute and moderately concentrated solutions of
MC3PVP blends, as well as the thermodynamic com-
patibility of these polymers and the physicomechanic-
al and thermomechanical properties of the films ob-
tained from their solutions.
Examination of the properties of MC3PVP blends
was motivated by a search for new modifiers of meth-
yl cellulose intended for encapsulation of medicines,
as well as by the possibility for preparing film ma-
terials containing PVP which, in turn, is suitable as
the basis for medicines.
The objects of our study were commercial samples
of MC with the degree of substitution of 1.7 and
molecular weight (MW) of 150 000 and PVP with
MW of 14200. The solutions of the MC3PVP blends
were prepared by mixing equiconcentrated solutions
of the two polymers at different component ratios.
Distilled water served as the solvent. The viscosity of
the dilute solutions was measured on an Ubbelohde
capillary viscometer at 20oC.
The rheological properties of moderately concen-
trated solutions (2 wt %) were studied on a Rheotest-
2.1 rheoviscometer at shear stresses within 33 600 Pa
at 20350oC. The gelation onset temperature T
solutions was determined from the change of the vis-
cosity of the solutions on a Hoeppler viscometer.