Prolonging Time to Flare in Pediatric Atopic Dermatitis: A Randomized, Investigator-Blinded, Controlled, Multicenter Clinical Study of a Ceramide-Containing Moisturizer

Prolonging Time to Flare in Pediatric Atopic Dermatitis: A Randomized, Investigator-Blinded,... Adv Ther (2017) 34:2601–2611 DOI 10.1007/s12325-017-0640-6 ORIGINAL RESEARCH Prolonging Time to Flare in Pediatric Atopic Dermatitis: A Randomized, Investigator-Blinded, Controlled, Multicenter Clinical Study of a Ceramide- Containing Moisturizer . . . . . Lin Ma Ping Li Jianping Tang Yifeng Guo Chunping Shen Jing Chang Nabil Kerrouche Received: September 9, 2017 / Published online: November 16, 2017 Springer Healthcare Ltd., part of Springer Nature 2017 were randomized to receive moisturizer twice ABSTRACT daily and body wash once daily, or body wash alone once daily for 12 weeks. The primary Introduction: Delaying or preventing flares is efficacy endpoint was time to flare [necessitat- important in atopic dermatitis (AD) manage- ing medical therapy and/or Investigator Global ment. The objective of the study was to evaluate Assessment (IGA)[1 (at least mild AD)]. Other whether using a ceramide-containing moistur- efficacy endpoints were AD characteristics and izer in addition to a body wash during latent AD emollient effects. The patient-reported outcome can delay flares. comprised satisfaction at week 12. The safety Methods: This was a randomized, investiga- endpoint was incidence of undesirable events. tor-blinded, parallel-group, controlled study Results: A total of 64 subjects aged 2–12 years among Chinese children with a history of mild http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Advances in Therapy Springer Journals

Prolonging Time to Flare in Pediatric Atopic Dermatitis: A Randomized, Investigator-Blinded, Controlled, Multicenter Clinical Study of a Ceramide-Containing Moisturizer

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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer Healthcare Ltd., part of Springer Nature
Subject
Medicine & Public Health; Internal Medicine; Oncology; Cardiology; Rheumatology; Endocrinology; Pharmacology/Toxicology
ISSN
0741-238X
eISSN
1865-8652
D.O.I.
10.1007/s12325-017-0640-6
Publisher site
See Article on Publisher Site

Abstract

Adv Ther (2017) 34:2601–2611 DOI 10.1007/s12325-017-0640-6 ORIGINAL RESEARCH Prolonging Time to Flare in Pediatric Atopic Dermatitis: A Randomized, Investigator-Blinded, Controlled, Multicenter Clinical Study of a Ceramide- Containing Moisturizer . . . . . Lin Ma Ping Li Jianping Tang Yifeng Guo Chunping Shen Jing Chang Nabil Kerrouche Received: September 9, 2017 / Published online: November 16, 2017 Springer Healthcare Ltd., part of Springer Nature 2017 were randomized to receive moisturizer twice ABSTRACT daily and body wash once daily, or body wash alone once daily for 12 weeks. The primary Introduction: Delaying or preventing flares is efficacy endpoint was time to flare [necessitat- important in atopic dermatitis (AD) manage- ing medical therapy and/or Investigator Global ment. The objective of the study was to evaluate Assessment (IGA)[1 (at least mild AD)]. Other whether using a ceramide-containing moistur- efficacy endpoints were AD characteristics and izer in addition to a body wash during latent AD emollient effects. The patient-reported outcome can delay flares. comprised satisfaction at week 12. The safety Methods: This was a randomized, investiga- endpoint was incidence of undesirable events. tor-blinded, parallel-group, controlled study Results: A total of 64 subjects aged 2–12 years among Chinese children with a history of mild

Journal

Advances in TherapySpringer Journals

Published: Nov 16, 2017

References

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