Prolonged survival in patients with breast cancer and a history of brain metastases: results of a preplanned subgroup analysis from the randomized phase III BEACON trial

Prolonged survival in patients with breast cancer and a history of brain metastases: results of a... Breast Cancer Res Treat (2017) 165:329–341 DOI 10.1007/s10549-017-4304-7 CLINICAL TRIAL Prolonged survival in patients with breast cancer and a history of brain metastases: results of a preplanned subgroup analysis from the randomized phase III BEACON trial 1 2 3 4 • • • • Javier Corte ´s Hope S. Rugo Ahmad Awada Chris Twelves 5 6 7 8 • • • • Edith A. Perez Seock–Ah Im Patricia Go ´ mez-Pardo Lee S. Schwartzberg 9 10 11 12 ´ • • • • Veronique Dieras Denise A. Yardley David A. Potter Audrey Mailliez 1 13 14 14 • • • • Alvaro Moreno-Aspitia Jin-Seok Ahn Carol Zhao Ute Hoch 14 15 16 • • Mary Tagliaferri Alison L. Hannah Joyce O’Shaughnessy Received: 12 May 2017 / Accepted: 16 May 2017 / Published online: 13 June 2017 The Author(s) 2017. This article is an open access publication Abstract those with treated, stable brain metastases. The primary Purpose Conventional chemotherapy has limited activity endpoint, overall survival (OS), was assessed in a pre-de- in patients with breast cancer and brain metastases fined subgroup of BCBM patients; an exploratory post hoc (BCBM). Etirinotecan pegol (EP), a novel long-acting analysis adjusting for the diagnosis-specific http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Breast Cancer Research and Treatment Springer Journals

Prolonged survival in patients with breast cancer and a history of brain metastases: results of a preplanned subgroup analysis from the randomized phase III BEACON trial

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Publisher
Springer US
Copyright
Copyright © 2017 by The Author(s)
Subject
Medicine & Public Health; Oncology
ISSN
0167-6806
eISSN
1573-7217
D.O.I.
10.1007/s10549-017-4304-7
Publisher site
See Article on Publisher Site

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