Progress and controversy in Bornavirus research: a meeting report

Progress and controversy in Bornavirus research: a meeting report Virology Division News 835 Arch Virol 144/4 (1999) Virology Division News VDN M. Schwemmle Institut für Medizinische Mikrobiologie und Hygiene, Freiburg, Federal Republic of Germany Introduction Borna disease virus (BDV) is the type species of a new family, Bornaviridae, within the nonsegmented negative-strand RNA viruses (Mononegavirales). Unlike other members of the order Mononegavirales BDV replicates and transcribes in the nucleus and uses the splicing machinery for modification of subgenomic RNAs. The host range includes a broad variety of warmblooded animals and most likely humans. BDV is neurotropic and infection of immunocompetent animals can result in Borna disease (BD), an immune-mediated brain disorder, characterised by prominent disturbances of movement and behaviour. First hints that BDV could also be associated with certain human diseases emerged from serological studies beginning in the 80’s when psychiatric patients were found to be seropositive in an indirect immunfluorescence assay (IFA). Ever since then, the question of whether BDV infections cause psychiatric disorders in humans has remained a controversial issue. An international meeting was held in Freiburg* to discuss progress and controversial topics in Bornavirus research. Among the highlights were aspects of the molecular biology of BDV, the neuropathology of BDV-infected animals and first reports on http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Progress and controversy in Bornavirus research: a meeting report

Loading next page...
 
/lp/springer_journal/progress-and-controversy-in-bornavirus-research-a-meeting-report-IimzmzYXoQ
Publisher
Springer-Verlag
Copyright
Copyright © Wien by 1999 Springer-Verlag/
Subject
Legacy
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s007050050549
Publisher site
See Article on Publisher Site

Abstract

Virology Division News 835 Arch Virol 144/4 (1999) Virology Division News VDN M. Schwemmle Institut für Medizinische Mikrobiologie und Hygiene, Freiburg, Federal Republic of Germany Introduction Borna disease virus (BDV) is the type species of a new family, Bornaviridae, within the nonsegmented negative-strand RNA viruses (Mononegavirales). Unlike other members of the order Mononegavirales BDV replicates and transcribes in the nucleus and uses the splicing machinery for modification of subgenomic RNAs. The host range includes a broad variety of warmblooded animals and most likely humans. BDV is neurotropic and infection of immunocompetent animals can result in Borna disease (BD), an immune-mediated brain disorder, characterised by prominent disturbances of movement and behaviour. First hints that BDV could also be associated with certain human diseases emerged from serological studies beginning in the 80’s when psychiatric patients were found to be seropositive in an indirect immunfluorescence assay (IFA). Ever since then, the question of whether BDV infections cause psychiatric disorders in humans has remained a controversial issue. An international meeting was held in Freiburg* to discuss progress and controversial topics in Bornavirus research. Among the highlights were aspects of the molecular biology of BDV, the neuropathology of BDV-infected animals and first reports on

Journal

Archives of VirologySpringer Journals

Published: Apr 1, 1999

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off