Prognostic factors affecting outcomes in fistulating perianal Crohn’s disease: a systematic review

Prognostic factors affecting outcomes in fistulating perianal Crohn’s disease: a systematic review Tech Coloproctol (2017) 21:501–519 DOI 10.1007/s10151-017-1647-3 REVIEW Prognostic factors affecting outcomes in fistulating perianal Crohn’s disease: a systematic review 1 1,2 3 2,3 • • • G. C. Braithwaite M. J. Lee D. Hind S. R. Brown Received: 1 February 2017 / Accepted: 22 May 2017 / Published online: 20 June 2017 The Author(s) 2017. This article is an open access publication Abstract mutations decreased response of fistulae to antibiotics. Background One in three patients with Crohn’s disease Complexity of fistulae anatomy was implicated in prog- will develop a perianal fistulae, and one third of these will nosis by 4 studies. achieve long-term healing or closure. A barrier to con- Conclusions This systematic review has identified potential ducting well-designed clinical trials for these patients is a prognostic markers, including genetic factors and disease lack of understanding of prognostic factors. This system- behaviour. We cannot, however, draw robust conclusions atic review sets out to identify factors associated with from this heterogeneous group of studies; therefore, we prognosis of perianal Crohn’s fistulae. recommend that a prospective cohort study of well-charac- Methods This review was registered on the PROSPERO terised patients with Crohn’s perianal fistulae is undertaken. database (CRD42016050316) and conducted in http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Techniques in Coloproctology Springer Journals

Prognostic factors affecting outcomes in fistulating perianal Crohn’s disease: a systematic review

Loading next page...
 
/lp/springer_journal/prognostic-factors-affecting-outcomes-in-fistulating-perianal-crohn-s-hdBZ6As2LG
Publisher
Springer International Publishing
Copyright
Copyright © 2017 by The Author(s)
Subject
Medicine & Public Health; Surgery; Gastroenterology; Proctology; Abdominal Surgery; Colorectal Surgery
ISSN
1123-6337
eISSN
1128-045X
D.O.I.
10.1007/s10151-017-1647-3
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial