Acta Neurol Belg (2017) 117:765–767 DOI 10.1007/s13760-016-0726-y LETTER TO THE EDITOR Primary central nervous system lymphoma of T-cell origin: an unusual cause of spinal cord disease 1 1 2 2 • • • • Sophie Fastre ´ Fre ´de ´ric London Julie Lelotte Alessandra Camboni Anne Jeanjean Received: 11 October 2016 / Accepted: 16 November 2016 / Published online: 23 November 2016 Belgian Neurological Society 2016 Introduction Case report Less than 1% of lymphomas are primary central nervous A 45-year-old Caucasian man without relevant medical system lymphomas (PCNSL) . Most of them are B-cell history developed progressive paraparesis and numbness of lineage and involve the supratentorial space, whereas his lower limbs over weeks, with bladder dysfunction. He T-cell origin and involvement of spinal cord are extre- had no systemic symptoms or fever. Clinical examination mely rare . Despite its rarity, primary spinal cord also revealed generalized hyperreﬂexia and bilateral exten- lymphoma (PSCL) of T-cell origin requires a meticulous sor plantar response. Brain and spinal cord magnetic reso- diagnosis, because delayed treatment can shorten survival. nance imaging (MRI) showed hypersignal on T2/FLAIR However, there are no typical clinical features or radio- images in left cerebellum and intramedullary cervical spinal logical
Acta Neurologica Belgica – Springer Journals
Published: Nov 23, 2016
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