Prevalence of cerebral cavernous malformations associated with developmental venous anomalies increases with age

Prevalence of cerebral cavernous malformations associated with developmental venous anomalies... Background and purpose To test the hypothesis that the prev- in prevalence of DVA-associated cavernous malformations alence of cerebral cavernous malformation (CCM) associated among patients with DVAs. These findings suggest that with developmental venous anomalies (DVAs) increases with DVA-associated cavernous malformations are acquired age, we studied the age-related prevalence of DVA-associated lesions. CCM among patients with DVAs. . . Materials and methods Patients with DVAs on contrast- Keywords Cavernous malformation Natural history . . enhanced MRI exams performed over a 2-year period were Developmental venous anomaly De novo Vascular included in this study. A single neuroradiologist reviewed all malformation imaging exams for the presence of CCMs. Baseline demo- graphic data collected included age, gender, presence of CNS neoplasm, history of cranial radiation, and history of Introduction seizure. Patients were divided into age groups based on de- cade of life. Cochran-Armitage trend tests were performed to The pathogenesis and timing of cerebral cavernous malforma- determine if increasing age was associated with CCM tion (CCM) development among patients with developmental prevalence. venous anomalies (DVAs) is unclear. Interestingly, up to 25% Results A total of 1689 patients with DVAs identified on of CCMs are associated with DVAs [1, 2] on standard se- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Child's Nervous System Springer Journals

Prevalence of cerebral cavernous malformations associated with developmental venous anomalies increases with age

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Medicine & Public Health; Neurosurgery; Neurosciences
ISSN
0256-7040
eISSN
1433-0350
D.O.I.
10.1007/s00381-017-3484-0
Publisher site
See Article on Publisher Site

Abstract

Background and purpose To test the hypothesis that the prev- in prevalence of DVA-associated cavernous malformations alence of cerebral cavernous malformation (CCM) associated among patients with DVAs. These findings suggest that with developmental venous anomalies (DVAs) increases with DVA-associated cavernous malformations are acquired age, we studied the age-related prevalence of DVA-associated lesions. CCM among patients with DVAs. . . Materials and methods Patients with DVAs on contrast- Keywords Cavernous malformation Natural history . . enhanced MRI exams performed over a 2-year period were Developmental venous anomaly De novo Vascular included in this study. A single neuroradiologist reviewed all malformation imaging exams for the presence of CCMs. Baseline demo- graphic data collected included age, gender, presence of CNS neoplasm, history of cranial radiation, and history of Introduction seizure. Patients were divided into age groups based on de- cade of life. Cochran-Armitage trend tests were performed to The pathogenesis and timing of cerebral cavernous malforma- determine if increasing age was associated with CCM tion (CCM) development among patients with developmental prevalence. venous anomalies (DVAs) is unclear. Interestingly, up to 25% Results A total of 1689 patients with DVAs identified on of CCMs are associated with DVAs [1, 2] on standard se-

Journal

Child's Nervous SystemSpringer Journals

Published: Jun 22, 2017

References

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