Backgrounds Chest low-dose CT screening (LDCTS) has been ﬁnding unprecedented numbers of peripheral non- small cell lung cancers (NSCLC) at an early stage and increased the number of patients with surgical indication. It is important to explore the inﬂuence of preoperative watchful–waiting time (WWT) on surgical outcomes. Objective is to clarify relationship between WWT and surgical outcomes of LDCTS-ﬁnding NSCLC from the view point of treatment delay. Methods Total 283 cases of NSCLC, found by LDCTS and consecutively resected, were surveyed for preoperative WWT and surgical outcomes. Validity of the present guideline for management of pulmonary nodules detected by LDCTS was veriﬁed whether WWT before surgery was suitable for eradication of NSCLC. Results The median value of WWT was 4.0 months in total, and the distribution of WWT exhibited long-tail-type pattern. That was 5.0 months in the group of pure ground-glass nodule (pGGN), 4.0 months in the group of part-solid nodule (PSN), and 1.7 months in the group of solid nodule (SON). During long-term postoperative observation time (median 79 months), 10-year progression-free survival rates were 100% in pGGN, 96% in PSN, and 72% in SON (P \ .0001). They decreased signiﬁcantly depending on enlargement of size: 91% or higher
World Journal of Surgery – Springer Journals
Published: Feb 28, 2018
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