Pregnancy-associated plasma protein-A (PAPP-A) as a possible biomarker in patients with coronary artery disease

Pregnancy-associated plasma protein-A (PAPP-A) as a possible biomarker in patients with coronary... Ir J Med Sci (2017) 186:597–605 DOI 10.1007/s11845-016-1515-6 ORIGINAL ARTICLE Pregnancy-associated plasma protein-A (PAPP-A) as a possible biomarker in patients with coronary artery disease 1 2 3 • • • H. Gutie ´rrez-Leonard E. Martı ´nez-Lara A. E. Fierro-Macı ´as 3 3 2 • • • V. M. Mena-Burciaga M. D. Ronquillo-Sa ´ nchez E. Floriano-Sa ´ nchez N. Ca ´ rdenas-Rodrı ´guez Received: 12 July 2016 / Accepted: 1 October 2016 / Published online: 11 October 2016 Royal Academy of Medicine in Ireland 2016 Abstract Results Coronary PAPP-A levels were slightly higher than Background Cardiovascular disease is the leading cause of peripheral PAPP-A levels (81.25 ± 2.34 and 62 ± 3 ng/ death in the Western world, and a major cause of this mL, respectively, P \ 0.0001); these levels were correlated disease is atherosclerosis. Research has demonstrated that with each other (r = 0.6629, P \ 0.001) but not with pregnancy-associated plasma protein A (PAPP-A) plays a clinicopathological factors (P [ 0.05). Coronary PAPP-A role in cardiovascular disease, as evidenced by the asso- levels were significantly elevated among patients at risk for ciation between PAPP-A and severity of heart damage. cardiovascular disease (P\ 0.05). Antioxidant enzyme Aim http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Irish Journal of Medical Science (1971 -) Springer Journals

Pregnancy-associated plasma protein-A (PAPP-A) as a possible biomarker in patients with coronary artery disease

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Publisher
Springer London
Copyright
Copyright © 2016 by Royal Academy of Medicine in Ireland
Subject
Medicine & Public Health; Internal Medicine; General Practice / Family Medicine
ISSN
0021-1265
eISSN
1863-4362
D.O.I.
10.1007/s11845-016-1515-6
Publisher site
See Article on Publisher Site

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