Ir J Med Sci (2017) 186:597–605 DOI 10.1007/s11845-016-1515-6 ORIGINAL ARTICLE Pregnancy-associated plasma protein-A (PAPP-A) as a possible biomarker in patients with coronary artery disease 1 2 3 • • • H. Gutie ´rrez-Leonard E. Martı ´nez-Lara A. E. Fierro-Macı ´as 3 3 2 • • • V. M. Mena-Burciaga M. D. Ronquillo-Sa ´ nchez E. Floriano-Sa ´ nchez N. Ca ´ rdenas-Rodrı ´guez Received: 12 July 2016 / Accepted: 1 October 2016 / Published online: 11 October 2016 Royal Academy of Medicine in Ireland 2016 Abstract Results Coronary PAPP-A levels were slightly higher than Background Cardiovascular disease is the leading cause of peripheral PAPP-A levels (81.25 ± 2.34 and 62 ± 3 ng/ death in the Western world, and a major cause of this mL, respectively, P \ 0.0001); these levels were correlated disease is atherosclerosis. Research has demonstrated that with each other (r = 0.6629, P \ 0.001) but not with pregnancy-associated plasma protein A (PAPP-A) plays a clinicopathological factors (P [ 0.05). Coronary PAPP-A role in cardiovascular disease, as evidenced by the asso- levels were signiﬁcantly elevated among patients at risk for ciation between PAPP-A and severity of heart damage. cardiovascular disease (P\ 0.05). Antioxidant enzyme Aim
Irish Journal of Medical Science (1971 -) – Springer Journals
Published: Oct 11, 2016
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera