Breast Cancer Res Treat (2017) 165:433–444 DOI 10.1007/s10549-017-4332-3 EPIDEMIOLOGY Preferences for breast cancer risk reduction among BRCA1/ BRCA2 mutation carriers: a discrete-choice experiment 1 2 3 4 • • • • Alexander Liede Carol A. Mansﬁeld Kelly A. Metcalfe Melanie A. Price 5,6 Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer 7 7 8 9 • • • • Carrie Snyder Henry T. Lynch Sue Friedman Justyna Amelio 2 3 10,11,12 • • • Joshua Posner Steven A. Narod Geoffrey J. Lindeman D. Gareth Evans Received: 1 June 2017 / Accepted: 6 June 2017 / Published online: 17 June 2017 The Author(s) 2017. This article is an open access publication Abstract of administration. Data were analyzed using a random- Purpose Unaffected women who carry BRCA1 or BRCA2 parameters logit model. Women were also asked to express mutations face difﬁcult choices about reducing their breast their preference between surgical and chemoprevention cancer risk. Understanding their treatment preferences options and to report on their actual risk-reduction actions. could help us improve patient counseling and inform drug Women aged 25–55 years with germline BRCA1/2 muta- trials. The objective was to explore preferences for various tions who were unaffected with breast
Breast Cancer Research and Treatment – Springer Journals
Published: Jun 17, 2017
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