Prednisone Reactions 1680, p285 - 2 Dec 2017 Steroid-induced psychosis: case report A 23-year-old woman developed steroid-induced psychosis during treatment with prednisone [route, dosage not stated]. The woman presented due to syncope with acute blood loss secondary to menorrhagia. After the presentation, she was diagnosed with lupus, and she received prednisone. Shortly after the prednisone therapy, she developed acute onset of anxiety, insomnia and command auditory hallucinations [duration of treatment to reaction onset not stated]. The woman’s prednisone therapy was therefore stopped and risperidone was started. Remission was achieved for one day, but she again developed psychiatric symptoms due to a lupus flare. The woman’s prednisone therapy was restarted at a lower dose along with antipsychotic medication. Thereafter, a complete remission was achieved and psychosis symptoms disappeared. Author comment: "Patient was started on prednisone and shortly thereafter developed acute onset of command auditory hallucinations, anxiety, and insomnia." " In our case example, we achieved the right combination of prednisone and an antipsychotic; symptoms remitted and the patient was successfully treated." Lieb K, et al. Case report of neuropsychiatric lupus versus steroid-induced psychosis in a young female: Mechanisms and management. CNS Spectrums 22: 81 (plus poster) abstr. 132, No. 1, Feb 2017. Available from: URL: http:// [abstract] - USA 803284804 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
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