Reactions 1704, p321 - 2 Jun 2018
Steroid-induced diabetes, delirium, electrolyte
imbalance and urinary tract infection: case report
A 91-year-old woman developed steroid-induced diabetes,
delirium, electrolyte imbalance and urinary tract infection
during treatment with prednisone for suspected giant cell
arteritis [route not stated; not all durations of treatment to
reactions onsets and outcomes stated].
The woman presented with photophobia and acute onset,
bilateral temporal headache of one day duration. On
examination, giant cell arteritis was suspected and prednisone
20mg once a day was started. She responded to the treatment
and felt better in a few days. However, she developed steroid-
The woman was treated with insulin. At week 10 of the
prednisone treatment, she needed a short hospitalisation due
to electrolyte imbalance, delirium and urinary tract infection.
Consequently, prednisone was quickly tapered off to reduce
further adverse effects. However, she developed weight loss,
poor appetite and skin infection following discontinuation of
prednisone. She was treated and a pulse of steroid was started.
Her vasculitis gradually improved. She was further treated with
a slow taper of prednisone with continued clinical and
laboratory monitoring. Eventually, she returned to baseline,
and insulin was stopped by nine months.
Author comment: "[S]he developed steroid-induced
diabetes and needed insulin during her treatment course. At
week 10 of prednisone, she was briefly hospitalized after
developing delirium, electrolyte disturbances and a urinary
tract infection. She was quickly tapered off prednisone to
minimize further adverse side effects. . ."
Larrain C, et al. Giant cell arteritis in the oldest old. Journal of the American
Geriatrics Society 66 (Suppl. 2): S19-S20 abstr. A23, Apr 2018. Available from:
URL: http://doi.org/10.1111/jgs.15376 [abstract] - USA
Reactions 2 Jun 2018 No. 17040114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved