Pragmatic approach to manage new oral anticoagulants in patients undergoing dental extractions: a prospective case-control study

Pragmatic approach to manage new oral anticoagulants in patients undergoing dental extractions: a... Objectives The aim of this study was to validate a standard- management of patients on NOACs undergoing dental extrac- ized pragmatic approach to manage new oral anticoagulants tion. Our pragmatic approach, omitting only a single morning (NOACs) in patients who undergo dental extractions. dose, can guide clinical practice. Both patients and physicians Materials and methods This prospective case-control study in should be aware of the increased delayed bleeding risk. patients undergoing dental extraction included 26 patients . . (mean age 76 years, 57% male) treated with dabigatran, Keywords Tooth extraction Anticoagulants New oral . . rivaroxaban, or apixaban and 26 matched controls. anticoagulants (NOACs) Interruption Bleeding Regardless of timing of extraction, drug regimen, or renal function, patients were instructed to skip only the dose on the morning of the procedure. A procedural bleeding score Introduction was recorded and early and delayed bleeding was assessed at day 1 and day 7. Bleeding events were compared with a Since the introduction of new oral anticoagulant drugs prospectively matched control group not taking any anti- (NOACs), the number of patients treated with this class of thrombotic drug. antithrombotics is steadily increasing. NOACs are indicated Results There was no difference in the procedural http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Oral Investigations Springer Journals

Pragmatic approach to manage new oral anticoagulants in patients undergoing dental extractions: a prospective case-control study

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2016 by Springer-Verlag Berlin Heidelberg
Subject
Dentistry; Dentistry
ISSN
1432-6981
eISSN
1436-3771
D.O.I.
10.1007/s00784-016-2010-1
Publisher site
See Article on Publisher Site

Abstract

Objectives The aim of this study was to validate a standard- management of patients on NOACs undergoing dental extrac- ized pragmatic approach to manage new oral anticoagulants tion. Our pragmatic approach, omitting only a single morning (NOACs) in patients who undergo dental extractions. dose, can guide clinical practice. Both patients and physicians Materials and methods This prospective case-control study in should be aware of the increased delayed bleeding risk. patients undergoing dental extraction included 26 patients . . (mean age 76 years, 57% male) treated with dabigatran, Keywords Tooth extraction Anticoagulants New oral . . rivaroxaban, or apixaban and 26 matched controls. anticoagulants (NOACs) Interruption Bleeding Regardless of timing of extraction, drug regimen, or renal function, patients were instructed to skip only the dose on the morning of the procedure. A procedural bleeding score Introduction was recorded and early and delayed bleeding was assessed at day 1 and day 7. Bleeding events were compared with a Since the introduction of new oral anticoagulant drugs prospectively matched control group not taking any anti- (NOACs), the number of patients treated with this class of thrombotic drug. antithrombotics is steadily increasing. NOACs are indicated Results There was no difference in the procedural

Journal

Clinical Oral InvestigationsSpringer Journals

Published: Nov 28, 2016

References

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