Ann Surg Oncol (2017) 24:2509–2517 DOI 10.1245/s10434-017-5867-6 OR IG INA L A R TIC L E – BREA S T O NC OLOG Y Population-Based Analysis of Breast Cancer Incidence and Survival Outcomes in Women Diagnosed with Lobular Carcinoma In Situ 1 2 1,3 4 Stephanie M. Wong, MD, MPH , Tari King, MD , Jean-Francois Boileau, MD, MSc , William T. Barry, PhD , and Mehra Golshan, MD 1 2 Department of Surgery, McGill University, Montreal, QC, Canada; Department of Surgery, Brigham and Women’s Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; Department of Surgery, Jewish General Segal Cancer Centre, Montreal, QC, Canada; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA ABSTRACT up of 8.1 years (range 0–30.9) a total of 1837 primary Purpose. A diagnosis of lobular carcinoma in situ (LCIS) breast cancers were diagnosed, of which 55.2% were is associated with an increased risk of developing breast diagnosed in the ipsilateral breast. Most breast cancers cancer, although little data exist on long-term patient out- were of low/intermediate grade, hormone receptor-positive, comes, including those who develop subsequent breast and diagnosed in early stages. Of subsequent malignancies, malignancies. invasive ductal carcinoma (IDC) distributed equally across
Annals of Surgical Oncology – Springer Journals
Published: Apr 28, 2017
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