Polymorphism of dental formula and segregation of its variants in a pedigree of Kerry Blue Terrier dogs

Polymorphism of dental formula and segregation of its variants in a pedigree of Kerry Blue... Polymorphism of the dental formula was analyzed in a complex pedigree of Kerry Blue Terrier. A lack of one or more lower premolars was observed in some dogs. Two different patterns of missing teeth were identified. One pattern consisted in agenesis of a second premolar, often in combination with agenesis of neighbor teeth, including the fourth premolar. In the second pattern, agenesis of a fourth premolar was expressed as an isolated abnormality. It was shown previously that the first pattern is inherited as a recessive trait with near complete penetrance. In this work, the major-gene control was demonstrated for the second pattern. This abnormality develops in 70–80% of mutant homozygotes and in no more than 20% of heterozygotes and wild-type homozygotes. It was shown that the two dentition abnormalities are controlled by different genes, which were designated LPA2 and LPA4 (Lower Premolar Agenesis). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Polymorphism of dental formula and segregation of its variants in a pedigree of Kerry Blue Terrier dogs

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Copyright © 2006 by Pleiades Publishing, Inc.
Biomedicine; Human Genetics; Microbial Genetics and Genomics; Animal Genetics and Genomics
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