Polyhydroquinolines: 1-sulfopyridinium chloride catalyzed an efficient one-pot multicomponent synthesis via Hantzsch condensation under solvent-free conditions

Polyhydroquinolines: 1-sulfopyridinium chloride catalyzed an efficient one-pot multicomponent... Keywords Hantzsch condensation  Polyhydroquinolines  Multicomponent reaction  Solvent-free conditions  1-Sulfopyridiniumchloride Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2559-y) contains supplementary material, which is available to authorized users. & B. Sakram bschemou@gmail.com Department of Chemistry, Osmania University, Hyderabad, Telangana State 500007, India 123 7652 B. Sakram et al. Introduction Multicomponent reactions (MCRs) are efficient synthetic tools for the construction of chemically and biological active compounds. They have unique advantages such as the generation of highly diverse and complex products from readily available substrates in a single synthetic operation without isolation of intermediates, and with maximum selectivity in minimal time, high atom economy, and high purity with excellent yields [1–3]. Nowadays, ionic liquid catalyzed reactions have gained considerable attention because of their interesting properties like high thermal stability, non-flammability, an ability to dissolve a wide range of materials, eco- friendly nature, and reusability, all contributing to carrying out reactions more effectively [4, 5]. Moreover, reactions under solvent-free conditions are also increasingly attractive to researchers due to the fact that without solvent, reactions usually need shorter reaction times, simpler reactors, and require simple and efficient workup procedures [6, 7]. 1,4-Dihydropyridine (1,4-DHP) derivatives are well known as calcium http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Polyhydroquinolines: 1-sulfopyridinium chloride catalyzed an efficient one-pot multicomponent synthesis via Hantzsch condensation under solvent-free conditions

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Publisher
Springer Netherlands
Copyright
Copyright © 2016 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-016-2559-y
Publisher site
See Article on Publisher Site

Abstract

Keywords Hantzsch condensation  Polyhydroquinolines  Multicomponent reaction  Solvent-free conditions  1-Sulfopyridiniumchloride Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2559-y) contains supplementary material, which is available to authorized users. & B. Sakram bschemou@gmail.com Department of Chemistry, Osmania University, Hyderabad, Telangana State 500007, India 123 7652 B. Sakram et al. Introduction Multicomponent reactions (MCRs) are efficient synthetic tools for the construction of chemically and biological active compounds. They have unique advantages such as the generation of highly diverse and complex products from readily available substrates in a single synthetic operation without isolation of intermediates, and with maximum selectivity in minimal time, high atom economy, and high purity with excellent yields [1–3]. Nowadays, ionic liquid catalyzed reactions have gained considerable attention because of their interesting properties like high thermal stability, non-flammability, an ability to dissolve a wide range of materials, eco- friendly nature, and reusability, all contributing to carrying out reactions more effectively [4, 5]. Moreover, reactions under solvent-free conditions are also increasingly attractive to researchers due to the fact that without solvent, reactions usually need shorter reaction times, simpler reactors, and require simple and efficient workup procedures [6, 7]. 1,4-Dihydropyridine (1,4-DHP) derivatives are well known as calcium

Journal

Research on Chemical IntermediatesSpringer Journals

Published: May 2, 2016

References

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