Keywords Hantzsch condensation Polyhydroquinolines Multicomponent reaction Solvent-free conditions 1-Sulfopyridiniumchloride Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2559-y) contains supplementary material, which is available to authorized users. & B. Sakram firstname.lastname@example.org Department of Chemistry, Osmania University, Hyderabad, Telangana State 500007, India 123 7652 B. Sakram et al. Introduction Multicomponent reactions (MCRs) are efﬁcient synthetic tools for the construction of chemically and biological active compounds. They have unique advantages such as the generation of highly diverse and complex products from readily available substrates in a single synthetic operation without isolation of intermediates, and with maximum selectivity in minimal time, high atom economy, and high purity with excellent yields [1–3]. Nowadays, ionic liquid catalyzed reactions have gained considerable attention because of their interesting properties like high thermal stability, non-ﬂammability, an ability to dissolve a wide range of materials, eco- friendly nature, and reusability, all contributing to carrying out reactions more effectively [4, 5]. Moreover, reactions under solvent-free conditions are also increasingly attractive to researchers due to the fact that without solvent, reactions usually need shorter reaction times, simpler reactors, and require simple and efﬁcient workup procedures [6, 7]. 1,4-Dihydropyridine (1,4-DHP) derivatives are well known as calcium
Research on Chemical Intermediates – Springer Journals
Published: May 2, 2016
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