Arch Gynecol Obstet (2017) 296:405–419 DOI 10.1007/s00404-017-4429-2 REVIEW Polycystic ovary syndrome, adipose tissue and metabolic syndrome 1 2 3 • • • Alessandro P. Delitala Giampiero Capobianco Giuseppe Delitala 2 2 Pier Luigi Cherchi Salvatore Dessole Received: 21 February 2017 / Accepted: 12 June 2017 / Published online: 22 June 2017 Springer-Verlag GmbH Germany 2017 Abstract Conclusion The high prevalence of metabolic disorders Purpose Polycystic ovary syndrome (PCOS) is the most mainly related to insulin resistance and CVD risk factors in common endocrine disorder that affects women of repro- women with PCOS highlight the need for early lifestyle ductive age and is characterized by ovulatory dysfunction changes for reducing metabolic risks in these patients. and/or androgen excess or polycystic ovaries. Women with PCOS present a number of systemic symptoms in addition Keywords Polycystic ovary syndrome Adipose tissue to those related to the reproductive system. It has been Adipokines Metabolic syndrome Insulin resistance associated with functional derangements in adipose tissue, metabolic syndrome, type 2 diabetes, and an increased risk of cardiovascular disease (CVD). Background Methods A detailed literature search on Pubmed was done for articles about PCOS, adipokines, insulinresistance, and Hyperandrogenism represents the most common endocrine metabolic
Archives of Gynecology and Obstetrics – Springer Journals
Published: Jun 22, 2017
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