Polidocanol

Polidocanol Reactions 1704, p309 - 2 Jun 2018 Acute ischemic stroke: case report A 68-year-old woman developed acute ischaemic stroke following administration of polidocanol [dosage not stated]. The woman suddenly developed hemiplegia and numbness in her right arm 30 minutes after foam sclerotherapy. Prior to the event, she had received seven polidocanol foam injections into the varicose veins of her right leg. At the time of admission to the hospital, mild weakness in her right hand remained grasping 9kg and pinching 2kg. Her national institutes of health stroke scale (NIHSS) score was 3. Laboratory investigation revealed elevated D-dimer value (9.3 g/mL), but normal number of platelets and blood sugar value. She was diagnosed with acute ischaemic stroke. In response to this, she received treatment with IV recombinant tissue-type plasminogen activator (rt-PA) following 89 minutes of stroke onset. Venous ultrasonography of the lower extremities revealed venous thrombosis in her right soleus vein. Transesophageal echocardiography with the valsalva contrast test revealed a patent foramen ovale. The venous thrombosis did not change after rt-PA therapy. Right hand weakness gradually improved to grasp 30kg and to pinch 8kg, and she was discharged 13 days following the onset, with a modified rankin scale of 1, which was same as admission. Author comment: "Some ischemic stroke cases after foam sclerotherapy to the varicose veins were recently reported in patients with patent foramen ovale." Matsuzono K, et al. Tissue Plasminogen Activator to Treat a Stroke after Foam Sclerotherapy in a Woman with a Patent Foramen Ovale. Journal of Stroke and Cerebrovascular Diseases 27: e110-e112, No. 6, Jun 2018. Available from: URL: http://doi.org/10.1016/j.jstrokecerebrovasdis.2018.01.001 - Japan 803323083 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Polidocanol

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46952-1
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p309 - 2 Jun 2018 Acute ischemic stroke: case report A 68-year-old woman developed acute ischaemic stroke following administration of polidocanol [dosage not stated]. The woman suddenly developed hemiplegia and numbness in her right arm 30 minutes after foam sclerotherapy. Prior to the event, she had received seven polidocanol foam injections into the varicose veins of her right leg. At the time of admission to the hospital, mild weakness in her right hand remained grasping 9kg and pinching 2kg. Her national institutes of health stroke scale (NIHSS) score was 3. Laboratory investigation revealed elevated D-dimer value (9.3 g/mL), but normal number of platelets and blood sugar value. She was diagnosed with acute ischaemic stroke. In response to this, she received treatment with IV recombinant tissue-type plasminogen activator (rt-PA) following 89 minutes of stroke onset. Venous ultrasonography of the lower extremities revealed venous thrombosis in her right soleus vein. Transesophageal echocardiography with the valsalva contrast test revealed a patent foramen ovale. The venous thrombosis did not change after rt-PA therapy. Right hand weakness gradually improved to grasp 30kg and to pinch 8kg, and she was discharged 13 days following the onset, with a modified rankin scale of 1, which was same as admission. Author comment: "Some ischemic stroke cases after foam sclerotherapy to the varicose veins were recently reported in patients with patent foramen ovale." Matsuzono K, et al. Tissue Plasminogen Activator to Treat a Stroke after Foam Sclerotherapy in a Woman with a Patent Foramen Ovale. Journal of Stroke and Cerebrovascular Diseases 27: e110-e112, No. 6, Jun 2018. Available from: URL: http://doi.org/10.1016/j.jstrokecerebrovasdis.2018.01.001 - Japan 803323083 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

References

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