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Pneumococcal 13 valent crm197 vaccine conjugate

Pneumococcal 13 valent crm197 vaccine conjugate Reactions 1680, p278 - 2 Dec 2017 Pneumococcal 13 valent crm197 vaccine conjugate Vaccine failure leading to invasive pneumococcal disease: case report An 11-month-old girl developed invasive pneumococcal disease (IPD) due to vaccine failure following immunisation with pneumococcal 13 valent CRM197 vaccine conjugate [route, dosage and time to reaction onset not stated]. The girl presented to the clinic because of fever with acute onset. Her blood evaluations revealed leukopenia and elevated CRP. She was healthy previously. She was vaccinated with pneumococcal vaccination (PCV) of pneumococcal 7 valent CRM197 vaccine conjugate at two months of age. At three months and four months of age, she was vaccinated with pneumococcal 13 valent CRM197 vaccine conjugate. Her vital signs on admission revealed body temperature of 40.5 C, pulse rate of 188 beats/minute and RR of 65 /minute. Her level of consciousness was depressed according to the Glasgow Coma Scale (E2V3M5). Bilateral cervical adenopathy, bilateral tonsillitis with purulent exudates and white spots, and enlargement of liver and spleen were evident. The auscultation of the lungs revealed stridor during respiration. Her blood tests at hospitalisation revealed WBC count of 2960 /mL (neutrophils 0%; lymphocytes 89% and atypical lymphocytes 8%), RBC count of 385104/mL, platelet http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Pneumococcal 13 valent crm197 vaccine conjugate

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017

Pneumococcal 13 valent crm197 vaccine conjugate

Abstract

Reactions 1680, p278 - 2 Dec 2017 Pneumococcal 13 valent crm197 vaccine conjugate Vaccine failure leading to invasive pneumococcal disease: case report An 11-month-old girl developed invasive pneumococcal disease (IPD) due to vaccine failure following immunisation with pneumococcal 13 valent CRM197 vaccine conjugate [route, dosage and time to reaction onset not stated]. The girl presented to the clinic because of fever with acute onset. Her blood evaluations revealed leukopenia and elevated...
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References (1)

Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
DOI
10.1007/s40278-017-39209-7
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p278 - 2 Dec 2017 Pneumococcal 13 valent crm197 vaccine conjugate Vaccine failure leading to invasive pneumococcal disease: case report An 11-month-old girl developed invasive pneumococcal disease (IPD) due to vaccine failure following immunisation with pneumococcal 13 valent CRM197 vaccine conjugate [route, dosage and time to reaction onset not stated]. The girl presented to the clinic because of fever with acute onset. Her blood evaluations revealed leukopenia and elevated CRP. She was healthy previously. She was vaccinated with pneumococcal vaccination (PCV) of pneumococcal 7 valent CRM197 vaccine conjugate at two months of age. At three months and four months of age, she was vaccinated with pneumococcal 13 valent CRM197 vaccine conjugate. Her vital signs on admission revealed body temperature of 40.5 C, pulse rate of 188 beats/minute and RR of 65 /minute. Her level of consciousness was depressed according to the Glasgow Coma Scale (E2V3M5). Bilateral cervical adenopathy, bilateral tonsillitis with purulent exudates and white spots, and enlargement of liver and spleen were evident. The auscultation of the lungs revealed stridor during respiration. Her blood tests at hospitalisation revealed WBC count of 2960 /mL (neutrophils 0%; lymphocytes 89% and atypical lymphocytes 8%), RBC count of 385104/mL, platelet

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

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