A study was performed on a plaster containing capsaicin. This is a commercial product used in the treatment of lumbago or arthralgia in Japan. When applied to a failing flap after flap elevation, flap survival increases significantly in comparison with a control group. Furthermore, pretreatment of the skin for six hours before flap elevation also caused a significant increase in flap survival, despite the fact that there was no application after flap elevation. Plaster containing capsaicin is easily obtained at any time by anyone since it is a commercial product. It provides a steady topical administration of the drug, and allows a study of the flap survival to be undertaken.
European Journal of Plastic Surgery – Springer Journals
Published: Sep 1, 1997
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