Plasma Dynamic Viscosity Determined by NMR

Plasma Dynamic Viscosity Determined by NMR Applied Appl Magn Reson Magnetic Resonance https://doi.org/10.1007/s00723-018-1026-x ORIGINAL PAPER 1 1 Manuel Arsenio Lores Guevara  · Yulianela Mengana Torres  · 1 2 Juan C. García Naranjo  · Norberto Rodríguez Suárez  · 3 3 3 Lidia C. Suárez Beyries  · María A. Marichal Feliu  · Teresa Simón Boada  · 3 4 Inocente C. Rodríguez Reyes  · Jan Philippé Received: 16 March 2018 / Revised: 23 May 2018 © Springer-Verlag GmbH Austria, part of Springer Nature 2018 Abstract A nuclear magnetic resonance (NMR) based experimental procedure to determine the dynamic viscosity (η) in blood plasma solutions is presented. An equation relating η and the transverse proton magnetic relaxation rate (1 ∕T ) is obtained after considering plasma an extremely diluted water solution of albumin with no long range hydrodynamics interactions among macromolecules, and a fast exchange of water molecules between the free and associated water. Carr–Purcell– Meiboom–Gill pulse sequence was used to measure the transverse proton mag- netic relaxation time (T ) in a magnetic resonance console coupled to one homo- geneous magnetic system (0.095  T). A η value of 1.68 ± 0.08  mPa  s was obtained in 20 control samples, which statistically matched the value obtained in the same samples using an Ostwald viscometer (1.61 ± 0.04 mPa s). η was determined in 172 patients with multiple myeloma (2.47 ± 0.15  mPa  s) and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Applied Magnetic Resonance Springer Journals
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Publisher
Springer Vienna
Copyright
Copyright © 2018 by Springer-Verlag GmbH Austria, part of Springer Nature
Subject
Physics; Solid State Physics; Spectroscopy/Spectrometry; Atoms and Molecules in Strong Fields, Laser Matter Interaction; Physical Chemistry; Organic Chemistry
ISSN
0937-9347
eISSN
1613-7507
D.O.I.
10.1007/s00723-018-1026-x
Publisher site
See Article on Publisher Site

Abstract

Applied Appl Magn Reson Magnetic Resonance https://doi.org/10.1007/s00723-018-1026-x ORIGINAL PAPER 1 1 Manuel Arsenio Lores Guevara  · Yulianela Mengana Torres  · 1 2 Juan C. García Naranjo  · Norberto Rodríguez Suárez  · 3 3 3 Lidia C. Suárez Beyries  · María A. Marichal Feliu  · Teresa Simón Boada  · 3 4 Inocente C. Rodríguez Reyes  · Jan Philippé Received: 16 March 2018 / Revised: 23 May 2018 © Springer-Verlag GmbH Austria, part of Springer Nature 2018 Abstract A nuclear magnetic resonance (NMR) based experimental procedure to determine the dynamic viscosity (η) in blood plasma solutions is presented. An equation relating η and the transverse proton magnetic relaxation rate (1 ∕T ) is obtained after considering plasma an extremely diluted water solution of albumin with no long range hydrodynamics interactions among macromolecules, and a fast exchange of water molecules between the free and associated water. Carr–Purcell– Meiboom–Gill pulse sequence was used to measure the transverse proton mag- netic relaxation time (T ) in a magnetic resonance console coupled to one homo- geneous magnetic system (0.095  T). A η value of 1.68 ± 0.08  mPa  s was obtained in 20 control samples, which statistically matched the value obtained in the same samples using an Ostwald viscometer (1.61 ± 0.04 mPa s). η was determined in 172 patients with multiple myeloma (2.47 ± 0.15  mPa  s) and

Journal

Applied Magnetic ResonanceSpringer Journals

Published: Jun 5, 2018

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