piRNAs and Evolutionary Trajectories in Genome Size and Content

piRNAs and Evolutionary Trajectories in Genome Size and Content J Mol Evol (2017) 85:169–171 DOI 10.1007/s00239-017-9818-4 LETTERS TO THE EDITOR piRNAs and Evolutionary Trajectories in Genome Size and Content Rachel Lockridge Mueller   Received: 19 October 2017 / Accepted: 30 October 2017 / Published online: 6 November 2017 © Springer Science+Business Media, LLC 2017 Transposable elements (TEs) are diverse sequences that Petrov 2002). Today, these explanations appear overly sim- move from one genomic locus to another using mechanisms plistic; they should be revisited, incorporating evolved dif- that include initiation of double-strand DNA breaks, integra- ferences in TE control pathways across species. However, to tion of sequences, and, for TEs with an RNA intermediate, date, relatively little research has focused on the evolution of reverse transcription (Craig et al. 2002). Novel TE inser- small RNA-based mechanisms of TE control (for examples, tions can disrupt protein function and gene expression. TE see Blumenstiel et al. 2016; Kelleher and Barbash 2013; sequences also cause ectopic recombination. Finally, TEs Madison-Villar et al. 2016). can sustain gain-of-function mutations, creating novel func- What challenges and opportunities exist in this emerging tional sequences (De Gobbi et al. 2006). Our understanding area? Many model organisms were chosen for their small, of TE diversity lags behind other portions of the genome, non-repetitive, and “tractable” genomes, but they provide http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Molecular Evolution Springer Journals

piRNAs and Evolutionary Trajectories in Genome Size and Content

Loading next page...
 
/lp/springer_journal/pirnas-and-evolutionary-trajectories-in-genome-size-and-content-IqcERfLQ1P
Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Life Sciences; Evolutionary Biology; Microbiology; Plant Sciences; Plant Genetics and Genomics; Animal Genetics and Genomics; Cell Biology
ISSN
0022-2844
eISSN
1432-1432
D.O.I.
10.1007/s00239-017-9818-4
Publisher site
See Article on Publisher Site

Abstract

J Mol Evol (2017) 85:169–171 DOI 10.1007/s00239-017-9818-4 LETTERS TO THE EDITOR piRNAs and Evolutionary Trajectories in Genome Size and Content Rachel Lockridge Mueller   Received: 19 October 2017 / Accepted: 30 October 2017 / Published online: 6 November 2017 © Springer Science+Business Media, LLC 2017 Transposable elements (TEs) are diverse sequences that Petrov 2002). Today, these explanations appear overly sim- move from one genomic locus to another using mechanisms plistic; they should be revisited, incorporating evolved dif- that include initiation of double-strand DNA breaks, integra- ferences in TE control pathways across species. However, to tion of sequences, and, for TEs with an RNA intermediate, date, relatively little research has focused on the evolution of reverse transcription (Craig et al. 2002). Novel TE inser- small RNA-based mechanisms of TE control (for examples, tions can disrupt protein function and gene expression. TE see Blumenstiel et al. 2016; Kelleher and Barbash 2013; sequences also cause ectopic recombination. Finally, TEs Madison-Villar et al. 2016). can sustain gain-of-function mutations, creating novel func- What challenges and opportunities exist in this emerging tional sequences (De Gobbi et al. 2006). Our understanding area? Many model organisms were chosen for their small, of TE diversity lags behind other portions of the genome, non-repetitive, and “tractable” genomes, but they provide

Journal

Journal of Molecular EvolutionSpringer Journals

Published: Nov 6, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off