1,4-Naphthoquinones exhibit strong activity as antimalarial, antibacterial, antifungal and anticancer agents. These kinds of compounds have also shown phytotoxic activity. The first example of an allelochemical to be described was naphthoquinone juglone (5-hydroxy-1,4-naphthoquinone). This fact led us to conduct a study of the phytotoxic activity and structure–activity relationships of 26 naphthazarin derivatives. The compounds belong to two main groups, 5,8-dioxygenated-1,4-naphthoquinones and 1,4,5,8-tetraoxygenated naphthalenes with different functionalizations and chains at positions 2, 4, 6 and 7. The results show that substitution with halogens and modification of the hydroxyl groups on the aromatic ring with methoxy or acetate groups seems to play an important role in enhancing the activity.
Research on Chemical Intermediates – Springer Journals
Published: Feb 11, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera