Access the full text.
Sign up today, get DeepDyve free for 14 days.
GJ Renukaradhya, X-J Meng, JG Calvert (2015)
Live porcine reproductive and respiratory syndrome virus vaccines: current status and future directionVaccine, 33
G Wensvoort, C Terpstra, JM Pol (1991)
Mystery swine disease in The Netherlands: the isolation of Lelystad virusVet Q, 13
HLX Vu, B Kwon, K-J Yoon (2011)
Immune evasion of porcine reproductive and respiratory syndrome virus through glycan shielding involves both glycoprotein 5 as well as glycoprotein 3J Virol, 85
R Allende, TL Lewis, Z Lu (1999)
North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regionsGen Virol, 80
ZZ Wei, T Lin, LC Sun (2012)
N-linked glycosylation of GP5 of porcine reproductive and respiratory syndrome virus is critically important for virus replication in vivoJ Virol, 86
I Trus, C Bonckaert, K Meulen, HJ Nauwynck (2014)
Efficacy of an attenuated European subtype 1 porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in pigs upon challenge with the East European subtype 3 PRRSV strain lenaVaccine, 32
Y Li, X Wang, P Jiang (2009)
Genetic variation analysis of porcine reproductive and respiratory syndrome virus isolated in China from 2002 to 2007 based on ORF5Vet Microbiol, 138
M Kearse, R Moir, A Wilson (2012)
Geneious basic: an integrated and extendable desktop software platform for the organization and analysis of sequence dataBioinformatics, 28
KD Rossow (1998)
Veterinary pathology onlineVet Pathol, 35
SE Midgley, K Banyai, J Buesa (2012)
Diversity and zoonotic potential of rotaviruses in swine and cattle across EuropeVet Microbiol, 156
KK Keffaber (1989)
Reproductive failure of unknown etiologyAm Assoc Swine Pract Newsl, 1
J-P Frossard, GJ Hughes, DG Westcott (2013)
Porcine reproductive and respiratory syndrome virus: genetic diversity of recent British isolatesVet Microbiol, 162
T Stadejek, MB Oleksiewicz, AV Scherbakov (2008)
Definition of subtypes in the European genotype of porcine reproductive and respiratory syndrome virus: nucleocapsid characteristics and geographical distribution in EuropeArch Virol, 153
KS Faaberg, JD Hocker, MM Erdman (2006)
Neutralizing antibody responses of pigs infected with natural GP5 N-glycan mutants of porcine reproductive and respiratory syndrome virusViral Immunol, 19
W Charerntantanakul (2012)
Porcine reproductive and respiratory syndrome virus vaccines: immunogenicity, efficacy and safety aspectsWorld J Virol, 1
EHJ Wissink, HAR Wijk, MV Kroese (2003)
The major envelope protein, GP5, of a European porcine reproductive and respiratory syndrome virus contains a neutralization epitope in its N-terminal ectodomainJ Gen Virol, 84
S Marozin, V Gregory, K Cameron (2002)
Antigenic and genetic diversity among swine influenza viruses in EuropeJ Gen Virol, 83
LK Kvisgaard, CK Hjulsager, CS Kristensen (2013)
Genetic and antigenic characterization of complete genomes of type 1 porcine reproductive and respiratory syndrome viruses (PRRSV) isolated in Denmark over a period of 10 yearsVirus Res, 178
T Dokland (2010)
The structural biology of PRRSVVirus Res, 154
Kim W Il, KJ Yoon (2008)
Molecular assessment of the role of envelope-associated structural proteins in cross neutralization among different PRRS virusesVirus Genes, 37
K Tamura, G Stecher, D Peterson (2013)
MEGA6: molecular evolutionary genetics analysis version 6.0Mol Biol Evol, 30
E Weiland, M Wieczorek-Krohmer, D Kohl (1999)
Monoclonal antibodies to the GP5 of porcine reproductive and respiratory syndrome virus are more effective in virus neutralization than monoclonal antibodies to the GP4Vet Microbiol, 66
Y Fang, P Schneider, WP Zhang (2007)
Diversity and evolution of a newly emerged North American Type 1 porcine arterivirus: analysis of isolates collected between 1999 and 2004Arch Virol, 152
XJ Meng, PS Paul, PG Halbur, I Morozov (1995)
Sequence comparison of open reading frames 2–5 of low and high virulence United States isolates of porcine reproductive and respiratory syndrome virusJ Gen Virol, 76
SL Ropp, CEM Wees, Y Fang (2004)
Characterization of emerging European-like porcine reproductive and respiratory syndrome virus isolates in the United StatesJ Virol, 78
IH Ansari, B Kwon, FA Osorio, AK Pattnaik (2006)
Influence of N-linked glycosylation of porcine reproductive and respiratory syndrome virus GP5 on virus infectivity, antigenicity, and ability to induce neutralizing antibodiesJ Virol, 80
MS Brar, M Shi, MP Murtaugh, FCC Leung (2015)
Evolutionary diversification of type 2 porcine reproductive and respiratory syndrome virusJ Gen Virol, 96
PGW Plagemann, RRR Rowland, KS Faaberg (2002)
The primary neutralization epitope of porcine respiratory and reproductive syndrome virus strain VR-2332 is located in the middle of the GP5 ectodomainArch Virol, 147
N Saitou, M Nei (1987)
The neighbour-joining method: a new method for reconstructing phylogenetic treesMol Biol Evol, 4
X Meng (2000)
Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine developmentVet Microbiol, 74
T Stadejek, A Stankevicius, MP Murtaugh, MB Oleksiewicz (2013)
Molecular evolution of PRRSV in Europe: current state of playVet Microbiol, 165
M Ostrowski, JA Galeota, AM Jar (2002)
Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus GP5 ectodomain identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus GPJ Virol, 76
L Gunn, PJ Collins, MJ O’Connell, H O’Shea (2015)
Phylogenetic investigation of enteric bovine coronavirus in Ireland reveals partitioning between European and global strainsIr Vet J, 68
P Pesente, V Rebonato, G Sandri (2006)
Phylogenetic analysis of ORF5 and ORF7 sequences of porcine reproductive and respiratory syndrome virus (PRRSV) from PRRS-positive Italian farms: a showcase for PRRSV epidemiology and its consequences on farm managementVet Microbiol, 114
To investigate the genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV) in Northern Ireland, the ORF5 gene from nine field isolates was sequenced and phylogenetically analysed. The results revealed relatively high diversity amongst isolates, with 87.6-92.2% identity between farms at the nucleotide level and 84.1-93.5% identity at the protein level. Phylogenetic analysis confirmed that all nine isolates belonged to the European (type 1) genotype and formed a cluster within the subtype 1 subgroup. This study provides the first report on PRRSV isolate diversity in Northern Ireland.
Archives of Virology – Springer Journals
Published: May 29, 2018
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.