Cardiovasc Intervent Radiol (2018) 41:1043–1048 https://doi.org/10.1007/s00270-018-1944-x CLINICAL INVESTIGATION INTERVENTIONAL ONCOLOGY Phase I/II Study of Radiofrequency Ablation for Painful Bone Metastases: Japan Interventional Radiology in Oncology Study Group 0208 1 2 3,4 5 • • • • Noboru Tanigawa Yasuaki Arai Koichiro Yamakado Takeshi Aramaki 6 7 8 9 • • • • Yoshitaka Inaba Susumu Kanazawa Osamu Matsui Masaya Miyazaki 10 11 12,13 • • Yoshihisa Kodama Hiroshi Anai Akihiro Hamanaka Received: 10 August 2017 / Accepted: 20 March 2018 / Published online: 12 April 2018 Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2018 Abstract 2 hypotension, and one patient developed Grade 1 burns at Purpose A prospective multicenter phase I/II trial was the grounding pad and puncture site. One patient died of performed to evaluate the clinical safety and efﬁcacy of liver failure on day 7 after RFA due to the progression of radiofrequency ablation (RFA) for metastatic bone tumors. the primary lesion. The efﬁcacy was excellent (no increase Materials and Methods Thirty-three patients (27 men, 6 in analgesic dosage, post-RFA VAS score of 0–2 or women, mean age 61 years) with metastatic bone tumors decreased by
CardioVascular and Interventional Radiology – Springer Journals
Published: Apr 12, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera