Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Richards, S. Lio, A. Sinha, K. Tieu, J. Sircar (2004)
Novel 2-(substituted phenyl)benzimidazole derivatives with potent activity against IgE, cytokines, and CD23 for the treatment of allergy and asthma.Journal of medicinal chemistry, 47 26
M. Tonelli, M. Simone, B. Tasso, F. Novelli, V. Boido, F. Sparatore, G. Paglietti, S. Pricl, G. Giliberti, Sylvain Blois, Cristina Ibba, G. Sanna, R. Loddo, P. Colla (2010)
Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives.Bioorganic & medicinal chemistry, 18 8
R. Arienzo, S. Cramp, H. Dyke, P. Lockey, D. Norman, A. Roach, Phil Smith, Melanie Wong, S. Wren (2007)
Quinazoline and benzimidazole MCH-1R antagonists.Bioorganic & medicinal chemistry letters, 17 5
N. Dege, M. Şekerci, S. Servi (2006)
Structure of 1-(Thiophen-2-ylmethyl)-2-(thiophen-2-yl)-1H-benzimidazoleTurkish Journal of Chemistry, 30
P. Beaulieu, M. Bös, Y. Bousquet, G. Fazal, J. Gauthier, J. Gillard, S. Goulet, S. LaPlante, M. Poupart, S. Lefèbvre, G. Mckercher, Charles Pellerin, V. Austel, G. Kukolj (2004)
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives.Bioorganic & medicinal chemistry letters, 14 1
Shin‐ichi Hirashima, Takahiro Oka, Kazutaka Ikegashira, S. Noji, H. Yamanaka, Yoshinori Hara, Hiroyuki Goto, R. Mizojiri, Yasushi Niwa, Toru Noguchi, Izuru Ando, S. Ikeda, Hiromasa Hashimoto (2007)
Further studies on hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors toward improved replicon cell activities: benzimidazole and structurally related compounds bearing the 2-morpholinophenyl moiety.Bioorganic & medicinal chemistry letters, 17 11
A. Rao, A. Chimirri, E. Clercq, A. Monforte, P. Monforte, C. Pannecouque, M. Zappalà (2002)
Synthesis and anti-hIV activity of 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole structurally-related 1,2-substituted benzimidazoles.Farmaco, 57 10
N. Meanwell, M. Krystal (2007)
Respiratory syncytial virus - The discovery and optimization of orally bioavailable fusion inhibitorsDrugs of The Future, 32
Kuo-long Yu, N. Sin, Rita Civiello, X. Wang, K. Combrink, H. Gulgeze, B. Venables, J. Wright, R. Dalterio, L. Zadjura, A. Marino, S. Dando, C. D’arienzo, K. Kadow, C. Cianci, Zhufang Li, J. Clarke, E. Genovesi, I. Medina, L. Lamb, R. Colonno, Zheng Yang, M. Krystal, N. Meanwell (2007)
Respiratory syncytial virus fusion inhibitors. Part 4: optimization for oral bioavailability.Bioorganic & medicinal chemistry letters, 17 4
K. McClure, Liming Huang, K. Arienti, F. Axe, A. Brunmark, J. Blevitt, J. Breitenbucher (2006)
Novel non-benzimidazole chk2 kinase inhibitors.Bioorganic & medicinal chemistry letters, 16 7
K. Arienti, A. Brunmark, F. Axe, K. McClure, Alice Lee, J. Blevitt, Danielle Neff, Liming Huang, Shelby Crawford, C. Pandit, L. Karlsson, J. Breitenbucher (2005)
Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles.Journal of medicinal chemistry, 48 6
M. Hranjec, G. Pavlović, M. Marjanović, M. Kralj, G. Karminski-Zamola, (2010)
Benzimidazole derivatives related to 2,3-acrylonitriles, benzimidazo[1,2-a]quinolines and fluorenes: synthesis, antitumor evaluation in vitro and crystal structure determination.European journal of medicinal chemistry, 45 6
S. Sondhi, R. Rani, Jaiveer Singh, P. Roy, S. Agrawal, A. Saxena (2010)
Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives.Bioorganic & medicinal chemistry letters, 20 7
Xianjin Luo, Zhong-wei Zhang, Yutian Yang, F. Xue, Naiyun Xiu, Yuanbin She (2009)
Design, synthesis, and antiviral properties of 2-aryl-1H-benzimidazole-4-carboxamide derivativesFrontiers of Chemical Engineering in China, 3
R. Frutos, I. Gallou, Diana Reeves, Yibo Xu, D. Krishnamurthy, C. Senanayake (2005)
Expedient synthesis of substituted imidazoles from nitrilesTetrahedron Letters, 46
M. Barreca, A. Chimirri, E. Clercq, L. Luca, A. Monforte, P. Monforte, A. Rao, M. Zappalà (2003)
Anti-HIV agents: design and discovery of new potent RT inhibitors.Farmaco, 58 3
M. Alamgir, D. Black, N. Kumar (2007)
Synthesis, Reactivity and Biological Activity of BenzimidazolesChemInform, 40
Aimin Song, Lucy Wu, Laura Ho, K. Lam (2006)
Facile solid-phase synthesis of 2,3-disubstituted 6H-pyrano[2,3-f]benzimidazole-6-onesTetrahedron, 62
K. Andries, M. Moeremans, Tom Gevers, R. Willebrords, C. Sommen, J. Lacrampe, F. Janssens, P. Wyde (2003)
Substituted benzimidazoles with nanomolar activity against respiratory syncytial virus.Antiviral research, 60 3
K. Starčević, M. Kralj, K. Ester, I. Sabol, M. Grce, K. Pavelić, G. Karminski-Zamola, (2007)
Synthesis, antiviral and antitumor activity of 2-substituted-5-amidino-benzimidazoles.Bioorganic & medicinal chemistry, 15 13
J. Bain, H. Mclauchlan, M. Elliott, P. Cohen (2003)
The specificities of protein kinase inhibitors: an update.The Biochemical journal, 371 Pt 1
M. Pagano, M. Andrzejewska, M. Ruzzene, S. Sarno, L. Cesaro, J. Bain, M. Elliott, F. Meggio, Z. Kazimierczuk, L. Pinna (2004)
Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole.Journal of medicinal chemistry, 47 25
A. Chimirri, S. Grasso, A. Monforte, P. Monforte, M. Zappalà (1991)
Anti-HIV agents II. Synthesis and in vitro anti-HIV activity of novel 1H,3H-thiazolo[3,4-a]benzimidazoles.Farmaco, 46 7-8
Yun He, Jun Yang, Baogen Wu, L. Risen, E. Swayze (2004)
Synthesis and biological evaluations of novel benzimidazoles as potential antibacterial agents.Bioorganic & medicinal chemistry letters, 14 5
R. Baudy, H. Fletcher, J. Yardley, M. Zaleska, D. Bramlett, R. Tasse, D. Kowal, A. Katz, and Moyer, M. Abou-Gharbia (2001)
Design, Synthesis, SAR, and Biological Evaluation of Highly Potent Benzimidazole-Spaced Phosphono-α-Amino Acid Competitive NMDA Antagonists of the AP-6 TypeJournal of Medicinal Chemistry, 44
M. Andrzejewska, L. Yépez-Mulia, R. Cedillo-Rivera, A. Tapia, L. Vilpo, J. Vilpo, Z. Kazimierczuk (2002)
Synthesis, antiprotozoal and anticancer activity of substituted 2-trifluoromethyl- and 2-pentafluoroethylbenzimidazoles.European journal of medicinal chemistry, 37 12
A. Palma, W. Heggermont, P. Leyssen, G. Pürstinger, Eva Wimmer, E. Clercq, A. Rao, A. Monforte, A. Chimirri, J. Neyts (2007)
Anti-enterovirus activity and structure-activity relationship of a series of 2,6-dihalophenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles.Biochemical and biophysical research communications, 353 3
Danielle Neff, Alice Lee-Dutra, J. Blevitt, F. Axe, M. Hack, Johnathan Buma, Raymond Rynberg, A. Brunmark, L. Karlsson, J. Breitenbucher (2007)
2-Aryl benzimidazoles featuring alkyl-linked pendant alcohols and amines as inhibitors of checkpoint kinase Chk2.Bioorganic & medicinal chemistry letters, 17 23
M. Pagano, F. Meggio, M. Ruzzene, M. Andrzejewska, Z. Kazimierczuk, L. Pinna (2004)
2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2.Biochemical and biophysical research communications, 321 4
Sabiha Alper, Ozlem Arpaci, Esin Aki, I. Yalcin (2003)
Some new bi- and ter-benzimidazole derivatives as topoisomerase I inhibitors.Farmaco, 58 7
M. Ramla, Mohamed Omar, H. Tokuda, H. El-Diwani (2007)
Synthesis and inhibitory activity of new benzimidazole derivatives against Burkitt's lymphoma promotion.Bioorganic & medicinal chemistry, 15 19
Juan Valdez, R. Cedillo, A. Hernández-Campos, Lilián Yépez, F. Hernández‐Luis, Gabriel Navarrete-Vázquez, A. Tapia, Rafael Cortés, Manuel Hernández, R. Castillo (2002)
Synthesis and antiparasitic activity of 1H-benzimidazole derivatives.Bioorganic & medicinal chemistry letters, 12 16
(2007)
Dalterio, L
Manohar Vedula, Aravinda Pulipaka, Chandrasekhar Venna, Vamsee Chintakunta, Sreenu Jinnapally, Venkata Kattuboina, Ravikrishna Vallakati, Vishnu Basetti, V. Akella, Sriram Rajgopal, A. Reka, Sravan Teepireddy, P. Mamnoor, R. Rajagopalan, Gopalakrishnan Bulusu, Akash Khandelwal, V. Upreti, Srinivas Mamidi (2003)
New styryl sulfones as anticancer agents.European journal of medicinal chemistry, 38 9
Shin‐ichi Hirashima, Takayoshi Suzuki, T. Ishida, S. Noji, Shinji Yata, Izuru Ando, M. Komatsu, S. Ikeda, Hiromasa Hashimoto (2006)
Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109.Journal of medicinal chemistry, 49 15
Ş. Demirayak, I. Kayağil, L. Yurttaş (2011)
Microwave supported synthesis of some novel 1,3-diarylpyrazino[1,2-a]benzimidazole derivatives and investigation of their anticancer activities.European journal of medicinal chemistry, 46 1
K. Combrink, H. Gulgeze, J. Thuring, Kuo-long Yu, Rita Civiello, Yi Zhang, B. Pearce, Z. Yin, D. Langley, K. Kadow, C. Cianci, Zhufang Li, J. Clarke, E. Genovesi, I. Medina, L. Lamb, Zheng Yang, L. Zadjura, M. Krystal, N. Meanwell (2007)
Respiratory syncytial virus fusion inhibitors. Part 6: an examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety.Bioorganic & medicinal chemistry letters, 17 17
Kuo-long Yu, X. Wang, Rita Civiello, A. Trehan, B. Pearce, Z. Yin, K. Combrink, H. Gulgeze, Yi Zhang, K. Kadow, C. Cianci, J. Clarke, E. Genovesi, I. Medina, L. Lamb, P. Wyde, M. Krystal, N. Meanwell (2006)
Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo.Bioorganic & medicinal chemistry letters, 16 5
Hideaki Hioki, K. Matsushita, M. Kubo, K. Harada, M. Kodama, Y. Fukuyama (2007)
Solid-phase combinatorial synthesis of benzothiazoles, benzimidazoles, and benzoxazoles using a traceless linkerTetrahedron, 63
S. El-Naem, A. El‐Nzhawy, H. El-Diwani, A. Hamid (2003)
Synthesis of 5‐Substituted 2‐Methylbenzimidazoles with Anticancer ActivityArchiv der Pharmazie, 336
P. Beaulieu, M. Bös, Y. Bousquet, Patrick DeRoy, G. Fazal, J. Gauthier, J. Gillard, S. Goulet, G. Mckercher, M. Poupart, Serge Valois, G. Kukolj (2004)
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency.Bioorganic & medicinal chemistry letters, 14 4
E. Novellino, B. Cosimelli, Marina Ehlardo, G. Greco, M. Iadanza, A. Lavecchia, M. Rimoli, A. Sala, A. Settimo, G. Primofiore, F. Settimo, S. Taliani, C. Motta, K. Klotz, D. Tuscano, M. Trincavelli, C. Martini (2005)
2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching.Journal of medicinal chemistry, 48 26
R. Ng, J. Guan, V. Alford, J. Lanter, G. Allan, Tifanie Sbriscia, S. Lundeen, Z. Sui (2007)
2-(2,2,2-Trifluoroethyl)-5,6-dichlorobenzimidazole derivatives as potent androgen receptor antagonists.Bioorganic & medicinal chemistry letters, 17 4
K. Biron (2006)
Antiviral drugs for cytomegalovirus diseases.Antiviral research, 71 2-3
K. Doležal, I. Popa, V. Kryštof, L. Spíchal, Martina Fojtíková, J. Holub, R. Lenobel, T. Schmülling, M. Strnad (2006)
Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells.Bioorganic & medicinal chemistry, 14 3
M. Ramla, Mohamed Omar, A. El-Khamry, H. El-Diwani (2006)
Synthesis and antitumor activity of 1-substituted-2-methyl-5-nitrobenzimidazoles.Bioorganic & medicinal chemistry, 14 21
D. Evers, Gloria Komazin, Do-Shik Shin, Debbie Hwang, L. Townsend, J. Drach (2002)
Interactions among antiviral drugs acting late in the replication cycle of human cytomegalovirus.Antiviral research, 56 1
M. Saulnier, David Frennesson, M. Wittman, K. Zimmermann, Upender Velaparthi, D. Langley, Charles Struzynski, Xiaopeng Sang, J. Carboni, Aixin Li, A. Greer, Zheng Yang, P. Balimane, M. Gottardis, R. Attar, D. Vyas (2008)
2-(1H-Imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924.Bioorganic & medicinal chemistry letters, 18 5
P. Hajduk, S. Boyd, D. Nettesheim, V. Nienaber, Jean Severin, R. Smith, D. Davidson, T. Rockway, S. Fesik (2000)
Identification of novel inhibitors of urokinase via NMR-based screening.Journal of medicinal chemistry, 43 21
A. Mollica, P. Davis, Shou-wu Ma, F. Porreca, J. Lai, V. Hruby (2006)
Synthesis and biological activity of the first cyclic biphalin analogues.Bioorganic & medicinal chemistry letters, 16 2
M. Wittman, J. Carboni, R. Attar, Balu Balasubramanian, P. Balimane, P. Brassil, F. Beaulieu, Chiehying Chang, W. Clarke, J. Dell, J. Eummer, David Frennesson, M. Gottardis, A. Greer, S. Hansel, W. Hurlburt, B. Jacobson, Subramaniam Krishnananthan, F. Lee, Aixin Li, Tai-an Lin, Peiying Liu, C. Ouellet, Xiaopeng Sang, M. Saulnier, K. Stoffan, Yax Sun, Upender Velaparthi, H. Wong, Zheng Yang, K. Zimmermann, M. Zoeckler, D. Vyas (2005)
Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity.Journal of medicinal chemistry, 48 18
Xiaojun Han, Sokhom Pin, K. Burris, Lawrence Fung, Stella Huang, M. Taber, Jie Zhang, G. Dubowchik (2005)
Synthesis and structure-activity relationship of imidazo[1,2-a]benzimidazoles as corticotropin-releasing factor 1 receptor antagonists.Bioorganic & medicinal chemistry letters, 15 18
(2006)
EL-Khamry, H.I. El-Diwani, Bioorg
M. Richards, S. Lio, A. Sinha, Homayon Banie, Richard Thomas, M. Major, Mark Tanji, J. Sircar (2006)
Substituted 2-phenyl-benzimidazole derivatives: novel compounds that suppress key markers of allergy.European journal of medicinal chemistry, 41 8
C. Kuş, G. Ayhan-Kilcigil, B. Eke, M. Iscan (2004)
Synthesis and antioxidant properties of some novel benzimidazole derivatives on lipid peroxidation in the rat liverArchives of Pharmacal Research, 27
L. Garuti, M. Roberti, G. Gentilomi (2001)
Synthesis and antiviral assays of some benzimidazole nucleosides and acyclonucleosides.Farmaco, 56 11
R. Ng, J. Guan, V. Alford, J. Lanter, G. Allan, Tifanie Sbriscia, Olivia Linton, S. Lundeen, Z. Sui (2007)
Synthesis and SAR of potent and selective androgen receptor antagonists: 5,6-Dichloro-benzimidazole derivatives.Bioorganic & medicinal chemistry letters, 17 3
M. Tonelli, G. Paglietti, V. Boido, F. Sparatore, F. Marongiu, Esther Marongiu, Paolo La Colla, R. Loddo (2008)
Antiviral Activity of Benzimidazole Derivatives. I. Antiviral Activity of 1‐Substituted‐2‐[(Benzotriazol‐1/2‐yl)methyl]benzimidazolesChemistry & Biodiversity, 5
S. Galal, K. Hegab, A. Hashem, N. Youssef (2010)
Synthesis and antitumor activity of novel benzimidazole-5-carboxylic acid derivatives and their transition metal complexes as topoisomerease II inhibitors.European journal of medicinal chemistry, 45 12
A. Abdel-Hafez (2007)
Benzimidazole condensed ring systems: New synthesis and antineoplastic activity of substituted 3,4-dihydro- and 1,2,3,4-tetrahydro-benzo [4,5]imidazo[1,2-a]pyrinnidine derivativesArchives of Pharmacal Research, 30
P. Beaulieu, Y. Bousquet, J. Gauthier, J. Gillard, M. Marquis, G. Mckercher, Charles Pellerin, Serge Valois, G. Kukolj (2004)
Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: inhibition of subgenomic hepatitis C virus RNA replicons in Huh-7 cells.Journal of medicinal chemistry, 47 27
Kuo‐Ting Huang, Chung‐Ming Sun (2002)
Liquid-phase combinatorial synthesis of aminobenzimidazoles.Bioorganic & medicinal chemistry letters, 12 7
Upender Velaparthi, Peiying Liu, Balu Balasubramanian, J. Carboni, R. Attar, M. Gottardis, Aixin Li, A. Greer, M. Zoeckler, M. Wittman, D. Vyas (2007)
Imidazole moiety replacements in the 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one inhibitors of insulin-like growth factor receptor-1 (IGF-1R) to improve cytochrome P450 profile.Bioorganic & medicinal chemistry letters, 17 11
S. Ozden, Dilek Atabey, S. Yıldız, H. Göker (2005)
Synthesis and potent antimicrobial activity of some novel methyl or ethyl 1H-benzimidazole-5-carboxylates derivatives carrying amide or amidine groups.Bioorganic & medicinal chemistry, 13 5
P. Beaulieu, J. Gillard, D. Bykowski, C. Brochu, N. Dansereau, J. Duceppe, B. Haché, A. Jakalian, L. Lagacé, S. LaPlante, G. Mckercher, Elaine Moreau, Stephane Perreault, Timothy Stammers, L. Thauvette, Jeffrey Warrington, G. Kukolj (2006)
Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: from benzimidazole to indole scaffolds.Bioorganic & medicinal chemistry letters, 16 19
Jun Cheng, Jiangtao Xie, Xianjin Luo (2005)
Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives.Bioorganic & medicinal chemistry letters, 15 2
J. Hwu, Raghunath Singha, S. Hong, Y. Chang, Asish Das, I. Vliegen, E. Clercq, J. Neyts (2008)
Synthesis of new benzimidazole-coumarin conjugates as anti-hepatitis C virus agents.Antiviral research, 77 2
(2006)
Goodman & Gilman’s The Pharmacological
X. Wang, C. Cianci, Kuo-long Yu, K. Combrink, J. Thuring, Yi Zhang, Rita Civiello, K. Kadow, Julia Roach, Zhufang Li, D. Langley, M. Krystal, N. Meanwell (2007)
Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity.Bioorganic & medicinal chemistry letters, 17 16
M. Wolff, W. Foye, R. Southgate, N. Osborne, M. Pearson, G. Burton, S. Beecham (1996)
BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY
Julie Charton, Sophie Girault-Mizzi, M. Debreu-Fontaine, F. Foufelle, I. Hainault, J. Bizot-Espiard, D. Caignard, C. Sergheraert (2006)
Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators.Bioorganic & medicinal chemistry, 14 13
N. Thimmegowda, S. Swamy, S. Swamy, C. Kumar, Y. Kumar, S. Chandrappa, G. Yip, K. Rangappa (2008)
Synthesis, characterization and evaluation of benzimidazole derivative and its precursors as inhibitors of MDA-MB-231 human breast cancer cell proliferation.Bioorganic & medicinal chemistry letters, 18 1
D. VanVliet, P. Gillespie, J. Scicinski (2005)
Rapid one-pot preparation of 2-substituted benzimidazoles from 2-nitroanilines using microwave conditionsTetrahedron Letters, 46
L. Goodman, A. Gilman (1976)
The Pharmacological Basis of TherapeuticsOptometry and Vision Science, 53
R. Ng, J. Lanter, V. Alford, G. Allan, Tifanie Sbriscia, S. Lundeen, Z. Sui (2007)
Synthesis of potent and tissue-selective androgen receptor modulators (SARMs): 2-(2,2,2)-Trifluoroethyl-benzimidazole scaffold.Bioorganic & medicinal chemistry letters, 17 6
X. Jing, Qi-Ming Zhu, Feng Xu, Xinfeng Ren, Dong Li, Chaoguo Yan (2006)
Rapid One‐Pot Preparation of 2‐Substituted Benzimidazoles from Esters using Microwave ConditionsSynthetic Communications, 36
T. Ishida, Takayoshi Suzuki, Shin‐ichi Hirashima, K. Mizutani, Atsuhito Yoshida, Izuru Ando, S. Ikeda, T. Adachi, Hiromasa Hashimoto (2006)
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole.Bioorganic & medicinal chemistry letters, 16 7
In recent years the synthesis of benzimidazole and its derivatives has attracted the attention of many organic chemists because of the compounds’ interesting biological activity and the crucial importance of the benzimidazole unit in the function of these biologically important molecules. Benzimidazole-based polyheterocyclic compounds have several interesting biological properties. Simple synthetic strategies leading to benzimidazole-based fused polyheterocyclic systems and the antiviral and anticancer biological activity of the compounds are surveyed in this review article.
Research on Chemical Intermediates – Springer Journals
Published: May 11, 2012
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.