J Cancer Res Clin Oncol (2017) 143:1823–1831 DOI 10.1007/s00432-017-2425-3 ORIGINAL ARTICLE – CLINICAL ONCOLOGY Personalized axillary dissection: the number of excised lymph nodes of nodal‑positive breast cancer patients has no significant impact on relapse‑free and overall survival 1 2 1 1 Florian Ebner · Achim Wöckel · Wolfgang Janni · Rolf Kreienberg · 1 3 Lukas Schwentner · Manfred Wischnewsky Received: 14 March 2017 / Accepted: 13 April 2017 / Published online: 24 April 2017 © Springer-Verlag Berlin Heidelberg 2017 Abstract RFS were intrinsic subtypes (p < 0.001) and tumor size Purpose Sentinel lymph node (SLN) biopsy has replaced (p < 0.001) and for OAS age (p < 0.001) and intrinsic sub- axillary lymph node dissection (ALND) for the staging of types (p < 0.001). There were no significant differences in clinically node-negative breast cancer patients (BCP), dem- RFS and OAS in any subgroup stratified by the number of onstrating equivalent survival to ALND while resulting in excised lymph nodes. Only for T3/T4 tumors, there is a reduced morbidity. ALND has remained the standard of very small significant advantage of ALND for RFS but not care for the majority of BCP with clinical axillary metasta- for OAS. After adjusting
Journal of Cancer Research and Clinical Oncology – Springer Journals
Published: Apr 24, 2017
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