J Clin Immunol (2017) 37:505–507 DOI 10.1007/s10875-017-0411-9 LETTER TO EDITOR Persistent Skin Pouches Following Subcutaneous Immunoglobulin Infusions in a Girl with Immunodeficiency, Bullous Skin Lesions and Melanosis Oculi 1,2 1 3 4 Renate Krüger & Cornelia Feiterna-Sperling & Ulrike Blume-Peytavi & Birgit Lala & 1,5,6,7 1 Horst von Bernuth & Volker Wahn Received: 25 November 2016 /Accepted: 7 June 2017 /Published online: 17 June 2017 Springer Science+Business Media, LLC 2017 Keywords S.C. Immunoglobulin Treatment adverse Patient History The girl was born to consanguineous Turkish effects inflammation parents (first degree cousins) after an uncomplicated pregnan- cy. Both parents, an older sister and brother were healthy. No other family members showed signs of skin disease or immu- To the Editor nodeficiency. The clinical findings of the patient were as Subcutaneous (s.c.) IgG replacement (SCIG) was introduced follows: in 1952 and is now frequently applied in patients with humoral Skin: The girl developed bullous skin lesions within the immunodeficiency (reviewed in ). Systemic adverse events first days of life, recurrent bullae appeared on extremities are rare, cutaneous side effects (swelling, redness) are com- and the trunk in the first years of life (Fig. 1 a) and mainly mon but mostly mild and
Journal of Clinical Immunology – Springer Journals
Published: Jun 17, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera