Persistence of anti-NMDAR antibodies in CSF after recovery from autoimmune encephalitis

Persistence of anti-NMDAR antibodies in CSF after recovery from autoimmune encephalitis Neurol Sci (2017) 38:1523–1524 DOI 10.1007/s10072-017-2958-x LETTER TO THE EDITOR Persistence of anti-NMDAR antibodies in CSF after recovery from autoimmune encephalitis 1 2 1 1 1 S. Mariotto & F. Andreetta & A. Farinazzo & S. Monaco & S. Ferrari Received: 16 December 2016 /Accepted: 6 April 2017 /Published online: 6 May 2017 Springer-Verlag Italia 2017 Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis activity. Blood tests noted only a severe hyponatremia and the is characterized by psychiatric and neuropsychiatric manifes- presence of low titer anti-thyroid peroxidase and thyroglobu- tations preceded by prodromal symptoms in about 70% of lin antibodies. CSF analysis showed lymphocytic pleocytosis patients. It can occur as an autoimmune antibody-mediated (360 cells/μL with 98% lymphocytes); extensive viral PCR and cultures ruled out an infectious etiology. She was treated non-paraneoplastic syndrome or as a paraneoplastic disorder, triggered by different tumors, more often an ovarian teratoma. with acyclovir and intravenous corticosteroids with a progres- NMDARs are localized in neuronal post-synaptic membranes sive tapering. At the end of February, CSF analysis revealed and play a role in synaptic transmission and plasticity. In vitro the presence of anti-NMDAR antibodies that were absent in and in vivo investigations confirm that anti-NMDAR antibod- serum. The patient http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neurological Sciences Springer Journals

Persistence of anti-NMDAR antibodies in CSF after recovery from autoimmune encephalitis

Loading next page...
 
/lp/springer_journal/persistence-of-anti-nmdar-antibodies-in-csf-after-recovery-from-udaNlrqxi0
Publisher
Springer Milan
Copyright
Copyright © 2017 by Springer-Verlag Italia
Subject
Medicine & Public Health; Neurology; Neuroradiology; Neurosurgery; Psychiatry
ISSN
1590-1874
eISSN
1590-3478
D.O.I.
10.1007/s10072-017-2958-x
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial