Ph Ph Ph H O HS O OH Pd(OAc)2 aq.NaBH4 RT 9-Decen-1-ol Pd Nanoparticle Ph N synthesis OH OH Ph & Murlidhar S. Shingare email@example.com Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431004, India 123 6696 R. R. Harale et al. Keywords 4-Thiazolidinones Cyclocondensation reaction Palladium nanoparticles Introduction 4-Thiazolidinone derivatives are of considerable and remarkable interest in the ﬁeld of medicinal chemistry. The 4-thiazolidinone heterocycles exhibit a wide range of biological activities such as anti-cancer , anti-malarial , anti-bacterial , anti- HIV  and nematicidal  activities, etc. Moreover, their end derivatives are also important precursors for the synthesis of useful pharmaceutical compounds, such as pyrazolothiazole derivatives , monoﬂuoro b-lactam  and also for the synthesis of polymethine cyanine dyes . Due to this diversity of the motif in the biological proﬁle, 4-thiazolidinones have attracted much attention of the research community to explore the catalytic pathways for its synthesis. The most recently used methods for the synthesis of thiazolidinone include condensation of aldehydes, anilines and mercaptoacetic acid using catalyst such as DCC , Saccharomyces cerevisiae , HBTU , [bmim][PF ], Bi(SCH COOH) , silica chloride , silica gel , etc. Attempts have also 2 3
Research on Chemical Intermediates – Springer Journals
Published: Mar 2, 2016
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