Parathyroid autotransplantation in thyroid surgery

Parathyroid autotransplantation in thyroid surgery Background Careful parathyroid gland dissection and in situ preservation was the time-honored approach to prevent parathyroid failure after total thyroidectomy. The relative success of parathyroid autotransplantation of hyperplastic parathyroid tissue in patients with renal or hereditary hyperparathyroidism did popularize the use of normal parathyroid tissue autografts during thyroidectomy to prevent permanent hypoparathyroidism. Proof of autograft function in this setting, however, is controversial. Purpose This narrative review aims at reviewing critically the current status of parathyroid autotransplantation during total thyroidectomy. It is also meant to analyze from the historical, methodological, and clinical points of view the claimed benefit of normal parathyroid gland autotransplantation. A focus is placed on the prevention of permanent hypoparathyroidism by parathyroid autotransplantation. Conclusions Liberal parathyroid autotransplantation was proposed in the mid 1970s but evidence of function is scarce. Proofs are accumulating that parathyroid autografts not only increase the rate of postoperative hypocalcemia, but may be also contribute to permanent hypoparathyroidism. . . . Keywords Thyroidectomy Parathyroid autotransplantation Hypoparathyroidism Preservation Parathyroid autotransplantation should not be used as a why the iPTH serum concentration falls below reference means of avoiding dissection no matter how long or values shortly after total thyroidectomy in a significant num- tedious. ber of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Langenbeck's Archives of Surgery Springer Journals

Parathyroid autotransplantation in thyroid surgery

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer-Verlag GmbH Germany, part of Springer Nature
Subject
Medicine & Public Health; General Surgery; Abdominal Surgery; Cardiac Surgery; Thoracic Surgery; Traumatic Surgery; Vascular Surgery
ISSN
1435-2443
eISSN
1435-2451
D.O.I.
10.1007/s00423-018-1654-5
Publisher site
See Article on Publisher Site

Abstract

Background Careful parathyroid gland dissection and in situ preservation was the time-honored approach to prevent parathyroid failure after total thyroidectomy. The relative success of parathyroid autotransplantation of hyperplastic parathyroid tissue in patients with renal or hereditary hyperparathyroidism did popularize the use of normal parathyroid tissue autografts during thyroidectomy to prevent permanent hypoparathyroidism. Proof of autograft function in this setting, however, is controversial. Purpose This narrative review aims at reviewing critically the current status of parathyroid autotransplantation during total thyroidectomy. It is also meant to analyze from the historical, methodological, and clinical points of view the claimed benefit of normal parathyroid gland autotransplantation. A focus is placed on the prevention of permanent hypoparathyroidism by parathyroid autotransplantation. Conclusions Liberal parathyroid autotransplantation was proposed in the mid 1970s but evidence of function is scarce. Proofs are accumulating that parathyroid autografts not only increase the rate of postoperative hypocalcemia, but may be also contribute to permanent hypoparathyroidism. . . . Keywords Thyroidectomy Parathyroid autotransplantation Hypoparathyroidism Preservation Parathyroid autotransplantation should not be used as a why the iPTH serum concentration falls below reference means of avoiding dissection no matter how long or values shortly after total thyroidectomy in a significant num- tedious. ber of

Journal

Langenbeck's Archives of SurgerySpringer Journals

Published: Feb 10, 2018

References

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