Acta Neurol Belg (2017) 117:741–742 DOI 10.1007/s13760-016-0727-x NEURO-IMAGES Paraneoplastic rhombencephalitis and cerebellitis preceded by isolated intractable vomiting 1 1 2 3 • • • • Dimitri Renard Giovanni Castelnovo Camille Bories Cecile Rieux Cindy Bernard-Decot Received: 20 August 2016 / Accepted: 18 November 2016 / Published online: 25 November 2016 Belgian Neurological Society 2016 Keywords Paraneoplastic Intractable Vomiting (Fig. 1). Whole body FDG-PET showed a hypermetabolic Emesis Gastroparesis pulmonary mass associated with hypermetabolic thoracic and cervical lymph nodes (Fig. 1). Blood and CSF para- neoplastic antibodies [Hu, Yo, Ri, amphiphysin, Ma1, Text Ma2, CV2, SOX1, and GAD65 (all analysed by immunoblotting; Laboratoire d’Immunologie, CHU Nıˆmes, A 59-year-old woman with active tobacco use presented France), TPO (analysed by electro-chemiluminescence with progressive intractable nausea and vomiting since immunoassay; Laboratoire de Biochimie, CHU Nıˆmes, 3 months, followed by progressive severe gait unsteadiness France), and LGI1 and CASPR2 (both tested by cell-based and uncoordinated limb movements. assay, HEK293 cells; Laboratoire d’Immunologie, CHU Clinical examination showed (asymptomatic) conjugate Lyon, France)] were absent. Biopsy of one of the cervical abnormal eye movements making eye ﬁxation impossible lymph nodes showed the presence of a small cell neu- and bilateral eye lid retraction
Acta Neurologica Belgica – Springer Journals
Published: Nov 25, 2016
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