P-Ph-Mediated Repression of the leg–arista–wing complexGene Transcription in Drosophila

P-Ph-Mediated Repression of the leg–arista–wing complexGene Transcription in Drosophila Preliminary analysis of the leg–arista–wing complex (lawc) gene region in the corresponding mutants revealed Pelement insertion in the transcribed region of this locus. To demonstrate the main role of P element insertion in the complex pleiotropic phenotypic effect of the lawc gene, a system using P-Ph chimeric protein and based on the P-mediated repression of the lawc in vivo transcription was applied. As a result, extreme lawc-mutant phenotypes were obtained and examined. The P-Ph-mediated decrease of the level of the lawc gene transcription was also demonstrated. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

P-Ph-Mediated Repression of the leg–arista–wing complexGene Transcription in Drosophila

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Publisher
Springer Journals
Copyright
Copyright © 2003 by MAIK “Nauka/Interperiodica”
Subject
Biomedicine; Human Genetics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1023/A:1023748120494
Publisher site
See Article on Publisher Site

Abstract

Preliminary analysis of the leg–arista–wing complex (lawc) gene region in the corresponding mutants revealed Pelement insertion in the transcribed region of this locus. To demonstrate the main role of P element insertion in the complex pleiotropic phenotypic effect of the lawc gene, a system using P-Ph chimeric protein and based on the P-mediated repression of the lawc in vivo transcription was applied. As a result, extreme lawc-mutant phenotypes were obtained and examined. The P-Ph-mediated decrease of the level of the lawc gene transcription was also demonstrated.

Journal

Russian Journal of GeneticsSpringer Journals

Published: Oct 7, 2004

References

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