Internal and Emergency Medicine (2018) 13:647–649 https://doi.org/10.1007/s11739-018-1865-3 IM - COMMENTARY Oxidative stress and inflammation: new molecular targets for cardiovascular diseases 1 1 1 1 Matteo Becatti · Amanda Mannucci · Niccolò Taddei · Claudia Fiorillo Received: 17 April 2018 / Accepted: 22 April 2018 / Published online: 1 June 2018 © SIMI 2018 Coronary artery disease (CAD) is the underlying condition Neutrophil extracellular traps (NETs) have been identified in most acute coronary events and the leading cause of death in 2004 as a new neutrophil pathogen-killing mechanism, in developed countries . The previous studies have shown and have been proven beneficial against infections [ 19]. that oxidative stress, a condition caused by an imbalance NETs are extracellular DNA fibers comprising histones and between reactive oxygen species (ROS) production and anti- neutrophil antimicrobial proteins. Extracellular DNA traps oxidant defense systems and closely associated with many are also observed in inflammatory but noninfectious dis - other chronic and acute disorders [2–12], contributes to the eases, like autoimmune diseases  or psoriasis . New initiation and progression of endothelial dysfunction and emerging data describe NETs as the key players of several atherogenesis . Indeed, ROS can damage every cell vascular diseases, such as acute coronary syndrome, stroke, component,
Internal and Emergency Medicine – Springer Journals
Published: Jun 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera