Overall Survival of Patients with Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma Treated with Nimotuzumab in the Real World

Overall Survival of Patients with Locally Advanced or Metastatic Esophageal Squamous Cell... Adv Ther (2017) 34:2638–2647 DOI 10.1007/s12325-017-0631-7 ORIGINAL RESEARCH Overall Survival of Patients with Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma Treated with Nimotuzumab in the Real World . . . Yaimarelis Saumell Lizet Sanchez Sandra Gonzalez . . . Ramo ´ n Ortiz Edadny Medina Yaima Gala ´ n Agustin Lage Received: August 28, 2017 / Published online: November 13, 2017 Springer Healthcare Ltd. 2017 locally advanced or metastatic esophageal ABSTRACT squamous cell carcinoma. Methods: A comparative and retrospective Introduction: Despite improvements in surgi- effectiveness study was performed. The 93 cal techniques and treatments introduced into patients treated with nimotuzumab were mat- clinical practice, the overall survival of patients ched, with use of propensity score matching, with esophageal squamous cell carcinoma with patients who received a diagnosis of locally remains low. Several epidermal growth factor advanced or metastatic squamous cell carci- receptor inhibitors are being evaluated in the noma of the esophagus in three Cuban pro- context of clinical trials, but there is little evi- vinces reported between 2011 and 2015 to the dence of effectiveness in real-world conditions. National Cancer Registry. The Kaplan–Meier This study aimed at assessing the effectiveness method was used to estimate event–time dis- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Advances in Therapy Springer Journals

Overall Survival of Patients with Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma Treated with Nimotuzumab in the Real World

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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer Healthcare Ltd.
Subject
Medicine & Public Health; Internal Medicine; Oncology; Cardiology; Rheumatology; Endocrinology; Pharmacology/Toxicology
ISSN
0741-238X
eISSN
1865-8652
D.O.I.
10.1007/s12325-017-0631-7
Publisher site
See Article on Publisher Site

Abstract

Adv Ther (2017) 34:2638–2647 DOI 10.1007/s12325-017-0631-7 ORIGINAL RESEARCH Overall Survival of Patients with Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma Treated with Nimotuzumab in the Real World . . . Yaimarelis Saumell Lizet Sanchez Sandra Gonzalez . . . Ramo ´ n Ortiz Edadny Medina Yaima Gala ´ n Agustin Lage Received: August 28, 2017 / Published online: November 13, 2017 Springer Healthcare Ltd. 2017 locally advanced or metastatic esophageal ABSTRACT squamous cell carcinoma. Methods: A comparative and retrospective Introduction: Despite improvements in surgi- effectiveness study was performed. The 93 cal techniques and treatments introduced into patients treated with nimotuzumab were mat- clinical practice, the overall survival of patients ched, with use of propensity score matching, with esophageal squamous cell carcinoma with patients who received a diagnosis of locally remains low. Several epidermal growth factor advanced or metastatic squamous cell carci- receptor inhibitors are being evaluated in the noma of the esophagus in three Cuban pro- context of clinical trials, but there is little evi- vinces reported between 2011 and 2015 to the dence of effectiveness in real-world conditions. National Cancer Registry. The Kaplan–Meier This study aimed at assessing the effectiveness method was used to estimate event–time dis-

Journal

Advances in TherapySpringer Journals

Published: Nov 13, 2017

References

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