Adv Ther (2017) 34:2638–2647 DOI 10.1007/s12325-017-0631-7 ORIGINAL RESEARCH Overall Survival of Patients with Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma Treated with Nimotuzumab in the Real World . . . Yaimarelis Saumell Lizet Sanchez Sandra Gonzalez . . . Ramo ´ n Ortiz Edadny Medina Yaima Gala ´ n Agustin Lage Received: August 28, 2017 / Published online: November 13, 2017 Springer Healthcare Ltd. 2017 locally advanced or metastatic esophageal ABSTRACT squamous cell carcinoma. Methods: A comparative and retrospective Introduction: Despite improvements in surgi- effectiveness study was performed. The 93 cal techniques and treatments introduced into patients treated with nimotuzumab were mat- clinical practice, the overall survival of patients ched, with use of propensity score matching, with esophageal squamous cell carcinoma with patients who received a diagnosis of locally remains low. Several epidermal growth factor advanced or metastatic squamous cell carci- receptor inhibitors are being evaluated in the noma of the esophagus in three Cuban pro- context of clinical trials, but there is little evi- vinces reported between 2011 and 2015 to the dence of effectiveness in real-world conditions. National Cancer Registry. The Kaplan–Meier This study aimed at assessing the effectiveness method was used to estimate event–time dis-
Advances in Therapy – Springer Journals
Published: Nov 13, 2017
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