Clin Oral Invest (2017) 21:2265–2272 DOI 10.1007/s00784-016-2019-5 ORIGINAL ARTICLE Osteogain® loaded onto an absorbable collagen sponge induces attachment and osteoblast differentiation of ST2 cells in vitro 1,2,3 1,4,5 6 Richard J. Miron & Masako Fujioka-Kobayashi & Yufeng Zhang & 7 8 9 10 Anton Sculean & Benjamin Pippenger & Yoshinori Shirakata & Umadevi Kandalam & Maria Hernandez Received: 5 October 2016 /Accepted: 23 November 2016 /Published online: 1 December 2016 Springer-Verlag Berlin Heidelberg 2016 Abstract matrix derivative (EMD) in combination with an absorbable Objectives Dimensional changes of the alveolar bone follow- collagen sponge (ACS) specifically designed for extraction ing tooth extraction are a major challenge in daily dental prac- socket healing. tice. To limit bone loss, a variety of biomaterials including Materials and methods The potential of ACS was first inves- bone grafts, barrier membranes, and growth factors have been tigated using ELISA to quantify total amelogenin adsorption utilized either alone or in combination therapies to increase the and release from 0 to 10 days. Thereafter, the cellular effects speed and quality of new bone formation. The aim of the of ST2 pre-osteoblasts were investigated for cellular attach- present in vitro study was to investigate the regenerative po- ment
Clinical Oral Investigations – Springer Journals
Published: Dec 1, 2016
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera