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Mammalian Genome 13, 120–122 (2002). DOI: 10.1007/s00335-001-3066-y Incorporating Mouse Genome © Springer-Verlag New York Inc. 2002 Orthologs of seven genes (AKT1, CDC42BPB, DIO3, EIF5, JAG2, KLC, NDUFB1) from human Chromosome 14q32 map to distal chicken Chromosome 5 Yvonne Boyd, Alison Haynes, Nat Bumstead Division of Molecular Biology, Institute for Animal Health, Compton, Newbury, Berks RG20 7NN, UK Received: 10 August 2001 / Accepted: 28 September 2001 Although birds and mammals diverged approximately 300 million total of 4.3 Mb of human genomic sequence) were analyzed and years ago, evolutionarily conserved chromosomal segments of annotated by using the NIX software available through the MRC similar gene contents can be discerned in the human and chicken HGMP Resource Centre website (http://www.hgmp.mrc.ac.uk). genomes (Burt et al. 1995, 1999; Girard-Santosuosso 1997). The Most of the genes identified were confirmed as lying in this region resolution of the human–chicken comparative map is limited by from human radiation hybrid maps (Deloukas et al. 1998), the the number of genes that have been mapped in the chicken genome human genome sequence annotated by ENSEMBL (http:// and is defined by approximately 350 loci (Groenen et al. 2000; www.ensembl.org) and the mouse genetic map for Chr 12 Schmid et
Mammalian Genome – Springer Journals
Published: Feb 15, 2014
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