Molecular diversity for the synthesis of pyran annulated heterocyclic scaffolds has been achieved from the multicomponent reaction of aldehyde, malonitrile and a third participant such as dimedone, barbituric acid and 3-methyl-1H-pyrazol-5(4H)-one. The reactions completed successfully using in situ-developed benzylidenemalononitriles via Knoevenagel reaction catalyzed by aspartic acid as a new efficient organo-catalyst in aqueous ethanol as a green medium at ambient conditions.
Research on Chemical Intermediates – Springer Journals
Published: Oct 19, 2016
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
All the latest content is available, no embargo periods.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud