Clin Oral Invest (2017) 21:2291–2301 DOI 10.1007/s00784-016-2022-x ORIGINAL ARTICLE Oral shedding of human herpesviruses in patients undergoing radiotherapy/chemotherapy treatment for head and neck squamous cell carcinoma 1 1 2 Michelle Palmieri & Victor Adriano de Oliveira Martins & Laura Masami Sumita & 2 1 Tania Regina Tozetto-Mendoza & Bruna Baraldi Romano & 2 2 3 Clarisse Martins Machado & Claudio Sergio Pannuti & Thaís Bianca Brandão & 3 1 1,2 Ana Carolina Prado Ribeiro & Luciana Corrêa & Paulo Henrique Braz-Silva Received: 3 June 2016 /Accepted: 30 November 2016 /Published online: 14 December 2016 Springer-Verlag Berlin Heidelberg 2016 Abstract Conclusions There was a positive correlation between EBV Objective Opportunistic infections may affect the oral mucosa oral shedding and oral mucositis grade ≥2, particularly after of patients undergoing radio/chemotherapy through exacerba- 3 weeks of radiotherapy, a period in which the severity of tion of oral mucositis. The aim of this study is to evaluate the mucositis was statistically higher. These findings allow us to oral shedding of all eight human herpesviruses and its possible infer that the local inflammatory environment in mucositis association with oral mucositis. grade ≥2 is more favorable for EBV replication. Materials and methods In this prospective
Clinical Oral Investigations – Springer Journals
Published: Dec 14, 2016
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