Clin Oral Invest (2017) 21:2371–2378 DOI 10.1007/s00784-016-2045-3 ORIGINAL ARTICLE Oral appliance therapy versus nasal continuous positive airway pressure in obstructive sleep apnea: a randomized, placebo-controlled trial on psychological distress 1 1 2 3 Ghizlane Aarab & Maria Nikolopoulou & Jari Ahlberg & Martijn W. Heymans & 4 5 1 Hans L. Hamburger & Jan de Lange & Frank Lobbezoo Received: 17 June 2016 /Accepted: 7 December 2016 /Published online: 12 January 2017 The Author(s) 2017. This article is published with open access at Springerlink.com Abstract between the therapy groups for the different dimensions of Objectives The aim of this randomized placebo-controlled the Symptom Checklist-90-Revised over time. trail was to compare the effects of an objectively titrated man- Results The MAD group showed significant improvements dibular advancement device (MAD) with those of nasal con- over time in the dimensions Bsomatization,^ Binsufficiency tinuous positive airway pressure (nCPAP) and an intraoral of thinking and acting,^ Bagoraphobia,^ Banxiety,^ Bsleeping placebo device on symptoms of psychological distress in problems,^ and Bglobal severity index^ (F =4.14–16.73, OSA patients. P =0.048–0.000). These improvements in symptoms of psy- Materials and methods In a parallel design, 64 mild/moderate chological distress were, however, not significantly different OSA patients (52.0
Clinical Oral Investigations – Springer Journals
Published: Jan 12, 2017
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