Background The ovarian cancer patients have good survival beneﬁt with optimal primary cytoreduction. Preoperative evaluation with imaging and tumour markers for the possibility of optimisation has been routinely practiced. Imaging though provides good insight about operability; the mesenteric, bowel and peritoneal surface diseases are not detected by imaging. The present study evaluates the role of Ca 125 in detecting optimisation in primary cytoreduction. Materials and Methods Prospective observational study of 194 patients of stage III epithelial ovarian cancer, with non- mucinous histology, was analyzed for the Ca 125 level in relation to optimisation. Results The statistical analysis of study results showed the p value of correlation between Ca 125 values, and residual disease was 0.7 which was statistically not signiﬁcant. Conclusion The results of the present study conclude that the serum Ca 125 levels do not correlate with the optimisation in cytoreduction. Keywords Optimal cyto reduction Tumour marker Residual disease Ovarian cancer Introduction prognosis. The Ca 125 values in epithelial ovarian cancer are in wide range. Few patients have values in normal Ca 125 also known as MUC 16 (mucin 16) encoded by range with few others having marked raise in the value of MUC16 gene
Indian Journal of Gynecologic Oncology – Springer Journals
Published: Feb 3, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
All the latest content is available, no embargo periods.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud