Can J Anesth/J Can Anesth (2018) 65:1004–1011 https://doi.org/10.1007/s12630-018-1165-4 REPORTS O F O RIGINAL I NVES TIGATIONS Optimal dose of intrathecal isobaric bupivacaine in total knee arthroplasty Dose optimale de bupivacaı¨ne intrathecale isobare dans l’arthroplastie totale de genou . . . Jeroen C. van Egmond, MD Hennie Verburg, MD Eveline A. Derks, MD . . . Pim N. J. Langendijk, PharmD Caner Ic¸li, BSc Nick T. van Dasselaar, MD, PhD Nina M. C. Mathijssen, PhD Received: 20 November 2017 / Revised: 11 April 2018 / Accepted: 18 April 2018 / Published online: 1 June 2018 Canadian Anesthesiologists’ Society 2018 Abstract pain. Time points of regaining motor and sensory functions Purpose Early mobilization is an important aspect of fast- were determined. track protocols and intrathecal bupivacaine is often used in Results Twenty-ﬁve patients were included. Mean (SD) primary total knee arthroplasty (TKA). Although the age was 70.1 (8.8) yr old, median [IQR] body mass index -2 optimal dose is not known, conventional doses leave was 29.5 [27.3-30.9 kgm ], and 48% were female. In 11 patients unable to mobilize for two to four hours. The dose patients the dose was inadequate; of these, nine patients of an intrathecally administered local anesthetic
Canadian Journal of Anesthesia/Journal canadien d'anesthésie – Springer Journals
Published: Jun 1, 2018
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