Purpose of Review The goal of this review is to provide an opportunistic invasive fungal infections in individuals with update on the epidemiology, diagnosis, and treatment of op- HIV/AIDS through different interventions: (a) continue to ex- portunistic fungal infections in patients with human immuno- pand the deployment of ART to the most affected populations deficiency virus (HIV) infection including Cryptococcus to achieve viral suppression; (b) ensure early diagnosis of spp., Histoplasma spp., Coccidioides spp., and Talaromyces fungal pathogen with point-of-care testing; (c) improve fungal marneffei,formerly Penicillium marneffei. diagnostic capacity in areas with the highest burden of AIDS- Recent Findings In many settings, despite increasing roll out related mycoses; and (d) increased availability of existing an- of antiretroviral therapy (ART), opportunistic invasive myco- tifungal drugs to optimally treat these infections. ses produce a substantial burden of disease. The prevalence of . . . specific fungal pathogens depends on their endemicity. Viral Keywords HIV/AIDS Cryptococcosis Histoplasmosis . . . suppression achieved by greater access to ART and increased Coccidioidomycosis Talaromycosis Penicilliosis the availability of point-of-care testing with rapid diagnostic AIDS-related mycoses tests (RDTs) aid to curtail the associated fungi morbidity. RDTs allow earlier screening to preemptively initiate treat- ment of opportunistic
Current Infectious Disease Reports – Springer Journals
Published: Aug 22, 2017
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