Opiorphin levels in fluids of burning mouth syndrome patients: a case-control study

Opiorphin levels in fluids of burning mouth syndrome patients: a case-control study Objectives Idiopathic Burning mouth syndrome (iBMS) is a ference in salivary opiorphin levels between iBMS and con- poorly understood affection characterized by persistent pain in trols does not favor a direct local role for opiorphin in the the oral cavity without any clinical or biological abnormality. etiopathogeny of iBMS. However, higher blood opiorphin Opiorphin is a natural inhibitor of enkephalin-inactivating levels may reflect a systemic dysregulation in iBMS. ectopeptidases, mainly produced by salivary glands, that has Trial registration demonstrated analgesic properties. The objective of the pres- NCT02686359 https://clinicaltrials.gov/ct2 ent case-control study was to test the hypothesis of a decrease /show/NCT02686359 in opiorphin levels in iBMS patients. . . . Materials and methods Twenty-one iBMS patients and 21 Keywords Burning mouth syndrome Opiorphin Saliva . . matched controls subjects were included between 2011 and Blood Urine Pain 2013. Submandibular and sublingual salivary, blood, and uri- nary opiorphin levels of iBMS patients were compared to controls. Introduction Results Results are expressed as mean values ± SD and com- pared using the Wilcoxon Signed Rank test. Correlations were Idiopathic Burning Mouth Syndrome (iBMS) also called analyzed with Spearman coefficient. The level of significance stomatodynia is a poorly understood affection characterized was fixed http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Oral Investigations Springer Journals

Loading next page...
Springer Berlin Heidelberg
Copyright © 2016 by Springer-Verlag Berlin Heidelberg
Dentistry; Dentistry
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial